The SAFER Self-Assessment Guide for Patient Identification in EHR Resilience helps healthcare organizations conduct self-assessments to optimize the safety and safe use of electronic health records (EHRs). This guide focuses on processes related to patient identification, including the creation of new patient records, patient registration, retrieval of information on previously registered patients, and other types of patient identification activities. The recommended practices can help prevent or detect and mitigate problems caused by duplicate records, patient mix-ups, and “comingled” (or “overlay”) records. The guide provides a Checklist and Practice Worksheets to help organizations prioritize EHR-related safety concerns and improve the overall safety of the healthcare system.