Analysis of Medical Research Studies

Recent studies have contributed significantly to our understanding of various medical conditions, treatments, and prevention strategies. Notable findings include the efficacy and safety of TEV-48125 in preventing high-frequency episodic migraine (Etzel et al., 2015), long-term outcomes after stenting versus endarterectomy for carotid stenosis (Bonati et al., 2015), and the impact of risk factors on specific causes of death among HIV-infected patients (Ingle et al., 2014). Additionally, research has shed light on the prevention of bone metastases in high-risk prostate cancer patients treated with zoledronic acid (Wirth et al., 2015) and the improvement of health-related quality of life and work productivity in chronic hepatitis C patients treated with ledipasvir and sofosbuvir (Younossi et al., 2015). These studies collectively demonstrate the importance of continued research in advancing our knowledge of various medical conditions and improving patient outcomes.

Promoting Lola’s
Independence
1

About Lola
Lola is the lady who took birth in the year 1939. She lives alone in a room and take care
of own self. She is active, positive mindset. She loves to do yoga ans she goes to art classes
regularly. She has excellent sense of humor and want to enjoy her life. She was the teacher and
got retired in the age of 69 from primary school. She went to Australia with her husband. She
suffered from Pneumonia in the year 2006, influenza in 2013 and more disease. Due to her age
she some times avoid to eat dinner but norm ally she eats it. She wants to be independence and
want to live her life with full of enjoyment.
Primary issues in the Lola are as :
 Hypertension
 Hearing loss
 Living alone
 Gord affects ability to work
Issue Key
Words
PHC Nursing
Intervention
Evidence Based
Practice Rationale
Effect Of Issue
On Lola’s
Comorbidities Or
Other Issues
Referral with
Rationale and
Links to Other
Issues.
Issue One
HTN
(Hypertensi
on)
The medicines that
are available for
improving Lola
from HNT are as
following:
Medicines
 ACE
inhibitors:
Lisinopril
and
valsartan.
 Calcium
channel
blockers-
diltiazem
and
verapamil
 Alpha-
blockers-
atenlol and
These treatments
are very effective
and can help in
controlling the
blood pressure of
the Lola. By this
way her health
will be improved.
Lisinopril and
verapamil
medicines are
much more
effective and it has
helped many other
patients those who
are suffering from
hyper tension. It
is found that
patients those are
above 60 years
Due to
hypertension
Lola can get
affected by heart
disease, heart
attacks, strokes,
heart failure,
kidney disease,
vascular
dementia, aortic
aneurysms (Wirth
and et.al, 2015).
Peripheral arterial
disease. These all
are those health
issues which can
create big trouble
to normal person.
Here Lola is old
lady and already
That can cause
harm to the body
parts of Lola and
due to this she
can lose her
mental level.
That would be
problematic for
the lady because
due to this her
Independence
will get affected
and no one will
talk to her from
society (Ford
and eta.l, 2014).
2

bisoprolo
 Renin
inhibitors-
Aliskiren
they should
consume 140 mm
Hg drug that
improve their
health
(Scarpignato and
et.al., 2015).
suffering from
many other
issues. So with
hypertension
major effects is
on her heart.
Heart attract is
very common
issues that can be
the reason of
death in old age
people.
Meditation is
another prevention
method for
protecting
independence of
Lola.
It is the main
treatment that help
in reducing
hypertension of
Lola.
Meditation is the
great therapy that
supports in
making mind relax
and that makes
control over
unnecessary
tensions
(Younossi and
et.al, 2015). It is
statistical fact that
persons those who
are doing
continuous
meditation they
live long life and
their well being
get improved. It
helps in
circulating the
blood in
systematic manner
and it increases
energy in human
being. So it can be
assumed that
meditation can
improve the
condition of Lola
and lady can be
confident by doing
meditation
regularly
(Dasgupta and
et.al, 2014).
Regular exercise is
the good prevention
Physical exercise
is the great way to
3

for Lola. improve health of
the Lola. It is
evidence from
past few years that
those persons who
are suffering from
HNT are doing
exercise and their
disease level has
been decreased to
large extent (Ingle
and et.al, 2014).
Maintaining health
weight
It is fact that
people those who
maintain their
body weight they
do not get suffered
from hyper
tension (Bonati.
and et.al, 2015).
By maintaining
the weight many
patients have been
recovered from his
disease.
Issue Two
Hearing
loss
Amplification
devices
Proper fitting of
the hearing aid can
assist the Lola in
getting out the
issue (Su and et.al,
2014). However It
is evident that the
54.202.105.233/P
MS
patient having
such issue can
experience
difficulties with
discrimination in
speech in situation
of greater noise.
Because of such
issue the patient
is not able to live
independent life
which is
influencing daily
working
(Anderson and
et.al, 2013). Also
this is resulting in
creating major
issues with which
well being of
Lola is getting
affected.
Amplification
device is creating
problem for the
Other issues that
are being faced
due to such is
inability to
interact to with
other people.
Along with this
such is creating
major issue in
making one
unable to work
in proper
manner
(Greenlee and
et.al, 2014).
Lip reading Reading of lips is
effective
4

technique for Lola
as this assist in
diminishing the
speech
discrimination
(Bigal and et.al,
2015). Further it is
effective for the
users who are
facing issues in
case of noisy
environment
Lola due to this
her independence
is getting affected
(Greenlee and
et.al, 2014).
Assistive devices
for listening
Such ranges from
the simple
amplification of
the telephone
signal to device
over the television
which is sending
the signal across
the room
(Goldstein and
et.al, 2015).
Cochlear implants
Issue Three
Living
alone
Yoga In order to remove
the feeling that is
attached with
living along yoga
is considered as
major treatment.
This helps one to
get out of the
situation that is
being faced by the
patient. At present
Lola is following
the same so as to
improve her well
being
Because of living
alone there is
presence of
several other
issues that are
being faced by
Lola. This can be
associated with
hypertension
(Vestbo and et.al,
2013). Getting
weakness as there
is no one to take
care of her. Thus
she has to cook
her food on own.
There is
existence of
several other
issues faced by
Lola that is no
interaction,
negative
attitude,
ineffective
behavior. Such
exists as a
reason of lack of
interaction.
Maintaining garden It is evident that
when one gets
involved in some
5

work then they
forget the
loneliness. Such is
effective for Lola
as well (Ingle and
et.al, 2014). This
is because through
such she can
divert her mind
towards other
things and can
work in proper
manner.
Walking from bus
stop on daily basis
This can be
considered as
important remedy
that can assist
Lola in getting out
of the situation
that is being faced
by her. Such will
help Lola in
increasing her
interaction which
can also assist her
in living an
independent life
(Wirth and et.al,
20150.
Carrying groceries Getting engaged
in certain work
would assist Lola
in working in an
effective manner.
Through this Lola
can have
independent life in
future course of
time (Bonati. and
et.al, 2015).
Issue Four
Gord
affects
ability to
Antacids It is evident that
use of such can
neutralize the
The issue related
with Gord has
resulted in
Other issues can
be change in the
life style
6

work
effect of stomach
acid in Lola
(Greenlee and
et.al, 2014).
several other
issues that
includes weight
loss, pain in
swallowing,
anaemia
because of
which Lola has
to avoid several
things. This has
greater impact
on her
independence
(Greenlee and
et.al, 2014.).
H2 Antagonists This has
suitability is
blocking the
effects of
chemical
histamine or some
cells within the
stomach.
Prorton pump
inhibitors
It is fact that such
is effective in
reducing the
amount of acid
that is being made
by stomach
Surgey This is needed in
very small number
people when there
is presence of
severity among
the patients. This
is evident in case
when the patient is
not getting relief
from the
medicines
(Greenlee and
et.al, 2014). This
is considered as
the last option that
is being adopted
by the patient who
is suffering from
the particular kind
of disease (Su and
et.al, 2014).
Detail description of the primary issues experienced by Lola
Hypertension is the disease in which blood pressure of the patients get increased. It is
most common disease which catch up with many of older age people (Greenlee and et.al, 2014).
7

It is major issue that is creating the problem for the older people and due to this their
interdependence is getting affected. Old people are unable o take care of themselves and due his
disease they need someone those who can take care them. But by this way they feel unable to
take their own decision and they have to depended on others. Calcium channel blockers-
diltiazem and verapamil, Alpha-blockers- atenlol and bisoprolo Renin inhibitors- Aliskiren are
some medicines which can help in improving their health. Meditation is another solution that can
help in improving their well being. It is statistical fact that people those who did regular exercise
and meditation they are now in good healthy position and are not suffering from the
hypertension. It is the issue that affect the well being of an individual and cause many other
problems within them. This is the major issue that affects Lola's independence and well being.
Due to loneliness, she is unable o discuss her problems with others and she can not share her
feelings as well. That is increasing her blood pressure level and creating severer problem of HNT
in the lady (Bigal and et.al, 2015). Due to this issue Lola is feeling very depressed and that harm
her situation to great extent. She is old person and due to hypertension she needs support of her
family. She is unable to make her decision by own. But as she is living alone in her room and
thee is no person who can take care of her. So this disease and issue is creating big trouble for
the Lola. This situation of Lola can be improved when she is offered with the opportunity to
share things with other people. This would remove her tension and would provide opportunity to
her to carry out her won on own and live in an independent manner (Vestbo and et.al, 2013).
Hearing loss is another issues that is being faced by Lola. Due to this she is facing
various other issue. Amplification devices can help the older people and can help in improving
their health. By giving them training of lip reading their well being can be improved soon. It is
the great technique that helps in protecting their independence and due to this they can live their
life in effective manner. H2 Antagonists is another great prevention method that helps in
improving the well being of the patients. It is found that many older people has living their life
now in better way with the help of this treatment. That makes them independent and they can
live their life happily and they do not have to be depended on others. Also it is obstructing the
Lola's ability live independent life. The loss of hearing can be cured when one possess the
equipment or possess the ability to read lips. With such Lola can improve her well being to a
greater extent. It is essential for Lola to work on such aspects as this would assist her in living
8

happy life. Major obstruction due to such is related with no interaction as she is unable to
understand what others are trying to say (Bonati. and et.al, 2015). This has greater demerit for
Lola and also she has no one to talk and have to live alone because of such. Hearing loss can
results in development of several other issues in vase of Lola as with such has independent living
as well as well being is hampered to a significant level.
Living alone is another issue that is being faced by Lola. This possess the ability to affect
her future and is influencing her per condition as well. This is the great issue that is problematic
for the older people. Old people want to discuss their feeling with others so that they can live
happyly. But loneliness is the major problem that affect their independence and that create
hypertension stitutaion for them. In such condition old people has to make interaction with the
society members so that they feel relaxed and it will refresh their mind and their well being will
get improved soon. Due to such there is no one who can take care of her in an effective manner.
In addition to this she has to cook her food on her own due to which is not able to take nutritional
diet (Anderson and et.al, 2013). It is important that for Lola to live independent life she must
interact with others so that she gets the opportunity to share her views with other person. Along
with this there is greater number of issues that Lola face because of living alone. With such she
do not get opportunity to get involve with others. Further she is not able to work in proper
manner as a reason of health problem. Thus greater number of difficulties are being faced by her
as a reason of this issue. The situation can be enhanced by the means of getting involved in
several activities that can provide her immense happiness. Along with this Lola needs to be
offered with greater care by health care practitioners so that she can work in proper manner and
enhancement can be bought in her living (Goldstein and et.al, 2015).
Gord affects ability to work is another issue that Lola is facing. This is kind of acidity
problem within the stomach that is affecting ability of Lola to work in proper manner. Such is
influencing the manner in which the work can be carried out in an independent manner. Because
of this Lola has to avoid various things that can be related with intake of something. Such is
influencing daily activities of Lola to a significant level. There are several medicines existing
that can help Lola in getting out of this situation in an effective manner. This has importance in
terms that it would help her in living independent life for longer duration of time. Further
improvement in such would assist her in enhancing her work performance (Scarpignato and
9

et.al., 2015). When proper dietary schedules is being complied with Lola then this issue can be
resolved which is of greater benefit to her. It is important for Lola to follow proper diet so that
she can come out of the situation in an effective manner. Lola's independence is being affected
by such factors and this is creating major issue for her. Also she is facing some other associated
issues as well which is obstructing her well being and living to a significant level. There is
greater importance of Lola to improve the health problem by taking own care as this has
effectiveness in making her live independent life effectively (Ford and eta.l, 2014).
Secondary issues in Lola
Lola likes to do humor and she lovers yoga. There are many other secondary issues which
is faced by the lady. She suffers from influenza it is in the family history so it is the secondary
issue in the lady. Shingles is another secondary issue from which she is suffering. It is the
infection of nerve and skin. It is caused by the virus called varicella zoster it can also emerge
disease in the human being of chickenpox. Body pain, rushes are common symptom of this
issue. So Lola is suffering from high body pain and she has rashes in her skin. Some times she
feels high fever and due to this she unable to take care of own. She is suffering from chronic
obstructive pulmonary disease and due to this she feels difficulty in breathing due to lung
problems.
Comorbidity
It is the medical term in which more diseases take place with the presence of primary
disease in the human being. Due to HTN she can suffer from heart problems, kidney issues.
Hypertension is the disease that weak the kidney and heart and person can get heart attack if
individual ignore their health. Hearing loss is the primary issue in the Lola that can give birth to
the tension and can destroy her life because due to hearing problem miscommunication can be
held. Due to this if someone says good then she feels unable to understand and that may cause
difficulty for her. Another issue which is faced by the Lola is Living alone and due to this she
has to make food for her own self. She is unable to share her feeling with others. It may cause
hypertension , her pulse rate can get increased and she may suffer from the heart attack. Due to
this her weight may get down and that is not good for her well being.
Principals of HA (High availability)
10

Elimination of single point of failure. Detection of failure as they occur and reliable
crossover are three principal of the HA.
11

REFERENCES
Books and Journals
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Bigal, M.E. and et.al., 2015. Safety, tolerability, and efficacy of TEV-48125 for preventive
treatment of high-frequency episodic migraine: a multicentre, randomised, double-blind,
placebo-controlled, phase 2b study. The Lancet Neurology. 14(11). pp.1081-1090.
Bonati, L. H. and et.al., 2015. Long-term outcomes after stenting versus endarterectomy for
treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS)
randomised trial. The Lancet. 385(9967). pp.529-538.
Dasgupta, K. and et.al., 2014. The 2014 Canadian Hypertension Education Program
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Su, K. P. and et.al., 2014. Omega-3 fatty acids in the prevention of interferon-alpha-induced
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13