This article discusses a qualitative and quantitative study on medication safety, exploring the aim, significance, methods, data analysis, results, limitations, and recommendations. The study utilized a semi-structured interview method and analyzed the collected data using MAXQDA10 software and SPSS version-20. The results identified three themes related to nurses' roles and responsibilities in medication safety, their ability to work safely, and acceptance of safety practices. The study recommends further research on the extensive roles of nurses with managers and the involvement of physicians and pharmacists in medication safety.