This article discusses the design of a Radio over Fiber system for a four-storey hospital building that has 15 rooms per floor. The system seeks to integrate the wireless radio system to the fiber optic communication technology. The article covers the system design and block diagram, system performance demonstrating the link budget of the designed system, system implementation on Optiwave and performance analysis, comparison of the performance of the designed system with simulated results, and the maximum number of channels that the system can accommodate.