This research proposal aims to explore the effectiveness of nanotechnology in the prevention, diagnosis, and treatment of cardiovascular diseases. It discusses the current trends and opinions among health professionals, the impact of nanotechnology on health outcomes in cardiovascular patients, and the need for new interventions. The proposed hypothesis is that nanotechnology is an effective cardiovascular intervention in terms of improvement of patient’s health outcomes, mortality of life, and overall quality of life as compared to traditional interventions such as oral medications or invasive heart surgeries. The research design is quantitative, retrospective, and cross-sectional, and the data will be collected through a survey and patient records. The data will be analyzed using Microsoft Excel, student’s t-test, and ANNOVA. The independent variables are cardiovascular interventions like nanotechnology, oral medications, and invasive surgery, while the dependent variables are mortality rates and quality of life scores. The sample will be collected using random and purpose sampling methods, and ethical considerations will be taken into account.