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Effectiveness of Nanotechnology in Cardiovascular Disease Prevention, Diagnosis and Treatment

Investigating the relationship between tooth restorative materials and plaque retention in a clinical study.

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Added on  2022-10-15

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This research proposal aims to explore the effectiveness of nanotechnology in the prevention, diagnosis, and treatment of cardiovascular diseases. It discusses the current trends and opinions among health professionals, the impact of nanotechnology on health outcomes in cardiovascular patients, and the need for new interventions. The proposed hypothesis is that nanotechnology is an effective cardiovascular intervention in terms of improvement of patient’s health outcomes, mortality of life, and overall quality of life as compared to traditional interventions such as oral medications or invasive heart surgeries. The research design is quantitative, retrospective, and cross-sectional, and the data will be collected through a survey and patient records. The data will be analyzed using Microsoft Excel, student’s t-test, and ANNOVA. The independent variables are cardiovascular interventions like nanotechnology, oral medications, and invasive surgery, while the dependent variables are mortality rates and quality of life scores. The sample will be collected using random and purpose sampling methods, and ethical considerations will be taken into account.

Effectiveness of Nanotechnology in Cardiovascular Disease Prevention, Diagnosis and Treatment

Investigating the relationship between tooth restorative materials and plaque retention in a clinical study.

   Added on 2022-10-15

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Research Proposal: EFFECTIVENESS OF
NANOTECHNOLOGY IN THE PREVENTION, DIAGNOSIS
AND TREATMENT OF CARDIOVASCULAR DISEASES
Effectiveness of Nanotechnology in Cardiovascular Disease Prevention, Diagnosis and Treatment_1
Introduction
• Approximately 17.6 million succumbed to
cardiovascular complications in 2016.
• Risk factors include with factors like obesity,
substance abuse, inactivity and inadequate diet
(World Health Organization, 2019).
• Despite traditional therapeutic interventions
cardiovascular diseases are still on the rise and
are associated with long term complications in
terms of daily life functionality and overall
health outcomes (Cooke & Atkins, 2016).
Effectiveness of Nanotechnology in Cardiovascular Disease Prevention, Diagnosis and Treatment_2
What is Nanotechnology?
• Nanotechnology can be defined as a novel and
innovative field of molecular science that
comprises of usage and manipulation of
substances and equipment at the nano scale
(Kuzmov & Minko, 2015).
• A major application for which nanoparticle
usage is considered to be exclusively effective
is the targeted delivery of drugs via both active
as well as passive method, for the purpose of
disease treatment (Cooke & Atkins, 2016).
Effectiveness of Nanotechnology in Cardiovascular Disease Prevention, Diagnosis and Treatment_3
Figure 1: Usage of nanoparticles for treatment of ischemia induced cardiac
injuries: A: Passive and active drug delivery targeting using enhanced
permeability and retention (EPR) effect and nanoparticles with targeting
moieties, B: Distribution of nanoparticles in biological systems to understand
their fat when administered in-vivo. (Source: Prajnamitra, R. P., Chen, H. C.,
Lin, C. J., Chen, L. L., & Hsieh, P. C. H. (2019). Nanotechnology Approaches in
Effectiveness of Nanotechnology in Cardiovascular Disease Prevention, Diagnosis and Treatment_4
Table 1: Summary of nanotechnology
applications in cardiovascular disease
Class Application
Liposome Thrombosis,
Atherosclerosis,
Vasodilation, Cardio-
protectant
Polymeric Nanoparticle Thrombosis,
Atherosclerosis, Cardio-
protectant
Polymeric micelle Thrombosis,
Atherosclerosis,
Vasodilation, Cardio-
protectant
Dendrimer Thrombosis,
Effectiveness of Nanotechnology in Cardiovascular Disease Prevention, Diagnosis and Treatment_5
Research Motives
• To explore the current trends and
opinions among health professionals on
the effectiveness of.
• To explore the effectiveness of
nanotechnology in improving the quality
of life in cardiac patients.
• To explore the effectiveness of
nanotechnology in improving the
mortality rate of cardiac patients.
Effectiveness of Nanotechnology in Cardiovascular Disease Prevention, Diagnosis and Treatment_6

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