EPIDEMIOLOGY 2EpidemiologyIntroductionEpidemiology is the study of the distribution and the determinant of health events in a population and its applications in solving health problems. This paper examines various area of epidemiology. These areas include study designs, measures of association, research analysis, biasand errors. These areas have been covered by means of answering given test questions.Question 1. a.The study is a prospective cohort study. The advantages of a prospective cohort study is that it can be used to calculate incidence of the disease and the risk of developing the outcome from the exposure. It is also suitable to study rare exposures. The study can also be used to study an exposure with multiple outcome (Wang & Clayton, 2006).b.Crude incidence rate is a of incidence that takes into account the time taken to observe the subjects. It incorporates time into the denominator. The denominator is usually in person-time units (Wang & Clayton, 2006)Crude incidence rate =numberofnewcasesofthedisease∈adefinedperiodoftimenumberofperson−timeunitatriskduringthedefinedperiodoftime =1879722419 = 0.0026 = 2.6 cases per 1000 person-year.
EPIDEMIOLOGY 3c.Quintile specific incidence rate = numberofnewcasesofdiseasewiththequantilenumberofperson−timeunitQuintile 1 = 392144698 = 2.7 per 1000 person-year Quintile 2 =352144403 = 2.4 per 1000 person-year Quintile 3 = 368144438 = 2.6 per 1000 person-year Quintile 4 = 358144471 = 2.5 per 1000 person-year Quintile 5 ¿405144409 = 2.8 per1000 person-year Quintile crude relative risk 2 = 0.86 x 0.43= 0.36983 = 0.85 x 0.83= 0.70554 =0.77 x 1.31
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