Proposal for Schizophrenia Genetic Testing

Running head: PROPOSAL
Milestone Three
Name of the Student
Name of the University
Author Note

1PROPOSAL
Introduction:
Topic-
Genetic testing or DNA testing refers to the procedure that encompasses the
determination of genetic diagnosis and bloodline, in relation to inherited disease
vulnerabilities. Schizophrenia is a complex disease that frequently appears in late life.
Although researchers have not outlined the genetic reasons, greater than 80% schizophrenia
onset are regarded to have a genetic cause (Ripke et al., 2014). The estimates usually vary
due to the problems that are faced in separating the environmental and genetic influences.
Research evidences have further shown that presence of a first-degree relative with the
condition is a major risk factor, besides monozygotic twins. This assignment will focus on
suggesting a proposal for schizophrenia genetic testing.
Summary of articles-
The inherited architecture of schizophrenia is compound and varied. Furthermore, it
involves a range of rare and common allelic variants. Childhood onset schizophrenia (COS)
is defined as rare AOS variant with superior familial aggregation of the disorder (Asarnow &
Forsyth, 2013). This establishes the need of utilizing genetic testing for diagnosis of the
condition. The article also elaborated on the prenatal complications that are found among
mothers diagnosed with schizophrenia, besides an upsurge in the risks of bearing children
having the same mental disorder. Another study that aimed to determine the extent of
correlation between cognition and schizophrenia suggested that community functioning and
cognition were positively correlated among schizophrenia patients and the genetic effects that
they shared. Thus, identification of genetic variants was considered useful for recognizing
individual differences (Kuo et al., 2018).

2PROPOSAL
Research hypothesis-
Genetic testing on persons with schizophrenia and cognitive incapacities allow
genetic psychologists to precisely predict whether a kid is going to have comparable
disabilities. The hypothesis has been derived following a thorough study of literature that
established the need to conduct further genetic testing, with the aim of assessing the
truthfulness behind its accuracy, as stated by doctors. There is mounting evidence for the fact
that schizophrenia is an extremely heritable disorder. The literature review conducted in the
preceding module helped in gaining an understanding on the correlation between cognition
and schizophrenia. The hypothesis was formulated following the identification of the need for
conducting an appropriate genetic testing in order to assess the accuracy of the truthfulness of
the procedure, as claimed by doctors.
Methods:
Methodology-
The research will be based on a quantitative archival design. Quantitative research
basically comprises of design of a project which practices quantitative research methods. The
primary feature of this research design is that quantitative research designs aim at
determining how many people act, think, or feel in a precise way. Quantitative projects
comprise of great sample sizes, focused on the amount of responses, as opposite to attainment
of an emotional insight that is the purpose of qualitative researches (Creswell & Creswell,
2017). Hence, the proposal is grounded on quantitative design owing to the fact that it will
allow for a broader study and will create provisions for greater accuracy and objectivity of
the results. The research will also be able to summarize the data collected from genetic
testing that will help in supporting the generalized hypothesis about the phenomenon
(schizophrenia) that is currently being investigated.