Sharon’s Case Study: Diabetes, Obesity, and Kidney Failure
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This essay assignment is a response to Sharon’s case study, focusing on her diagnosis of type II diabetes, obesity, and kidney failure. It discusses the risk factors, blood glucose levels, medication options, and nursing standards for practice.
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Sharon’s case study Introduction. The essay assignment is a response to Sharon’s case study. Sharon is a 58-year-old female patient with a height of 1.7 m and she weighs 120 kg. she also has a waist circumference of 110 cm. she has a past, medical history of type II diabetes mellitus which was diagnosed three years ago. She is currently under metformin to manage her diabetic condition. Sharon states that her usual blood glucose levels range from 8 mmol/L to 11 mmol/L throughout the whole day. When she wakes up in the morning her blood glucose levels read 7mmol/L to 8mmol/L. She is hypertensive with a systolic pressure of 140 mmHg and diastolic blood pressure 95 mmHg. For now, her consistent chronic kidney disease is evident with an eGFR of 85ml/minute and some proteinuria.The essay assignment will, therefore, be divided into five parts both of them responding to the case study described. Question 1 Sharon was diagnosed with diabetes type II. This type of diabetes is normally associated with lifestyle risk factors. Or it can be hereditarily inherited from one generation to the next generation. The risk factors related to the lifestyle include poor diet, physical activities which are not sufficient for the daily body requirement. Other risk factors are being obese or overweight. Sharon is obese with a Body Mass Index of 40.6 kg/m2. Her obesity is indicated by a BMI of above 30 kg/m2 and above (Bae et al 2016, pp 212-220). Her waist circumference of 110 cm also confirms her obesity since her waist circumference is more than 88 cm for her gender. Her age being above 40 years is an increased risk factor for her developing the type II diabetes mellitus(American Diabetes Association, 2017 pp. S11-S24). The diabetes mellitus a condition
characterized by high circulating blood sugar can lead to kidney failure. The kidney failure caused by diabetes mellitus takes some time for its signs and symptoms to manifest. With time the high blood glucose levels damage the kidney nephrons leading to kidney nephropathy which can progress to kidney failure(Reidy et al 2014, pp.2333-2340). The kidneys affected by diabetic nephropathy cease to work efficiently resulting in water and salt retention that raises the blood pressure rendering the client hypertensive. The renin-angiotensin system which regulate the blood pressure is thought to be involved in the development of diabetic nephropathy. People with diabetes have a high risk of developing hypertension(Hall et al 2014, p 75). In return, the hypertension is a risk factor forkidney disease development. Many arteries supply the blood containing the waste products and the fluid to be filtered by the kidney at the glomerular filtration site. Over time, if the high blood pressure is not managed it causes narrowing of the arteries supplying the blood to the kidney for filtration. The arteries become weak too and the excess glucose deposited harden the arteries with time too. They, therefore, become unable to deliver enough blood to the kidney and that is the onset of the kidney failure. Question 2 Sharon reports usual blood glucose levels of 8 to 10 mmol/L throughout the whole day. These blood glucose levels are higher. The normal glucose levels in a day should be between 3.2mmol/L to 6.5 mmol/L (Nankervis et al 2014). Sharon also states her morning blood glucose levels ranging from 7 mmol/L to 8 mmol/L. her glucose level should, therefore, be managed to be maintained at the normal ranges.
Question 3 Glucovance is a drug used to control high blood sugar levels in patients with type II diabetes mellitus(Prabhakar,Kumar&Doble2014,pp123-130).Glyburideasacomponentof Glucovance, it lowers blood sugar levels by allowing the release of the natural insulin into circulation and at the same time decreasing the amount of sugar made by the liver. By doing so it decreases the levels of the circulating blood glucose. On the other hand, metformin’s mechanism of action is decreasing the amount of sugar made by the liver and decreasing the amount of glucose absorbed by the stomach and the intestines.The interaction between the two drugs is synergistic. The therapeutic outcome of the two drugs used together is greater compared to the therapeutic outcome of each drug used individually(Foucquier & Guedj, 2015) Question 4 Currently, Sharon can be diagnosed with two medical conditions. Kidney failure which started as diabetic nephropathy. Kidneys filter blood from the arteries. When diabetes damages the arteries by depositing the excess sugar in them lead to damaging the kidneys as well.The second medical condition that can be diagnosed is the type II diabetes mellitus caused by the excess circulating glucose in the blood. Sharon is hypertensive, hypertension is related to diabetes mellitus and related to kidney failure as well. two drugs that can be invented should manage hypertension and the kidney nephropathy for them to be effective. The first drug should be clinically indicated for hypertension. This drug named as "vasonapril" should work aiming at blocking Angiotensin II. Angiotensin II promotes the secretion of aldosterone. Angiotensin II produced by the body tightens the blood vessels causing
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vasoconstriction increasing the blood pressure inside the vessels rising(Majumder & Wu, 2015, pp 256-283). When the Angiotensin II is blocked it will, therefore, cause relaxation of the blood vessels thus decreasing the pressure of the circulating blood inside the blood vessels. The second drug that can be administered should aim at managing the overweight and decreasing the waist circumference of Sharon. From the assessment data, it is evident that Sharon is overweight with a waist circumference of 110 cm this is above the normal waist circumference which is supposed to be 80 to 88 cm(Ashwell, M. and Gibson, S., 2016). Sharon also has a Body Mass Index of 40.6 which is higher than the normal BMI which is supposed to be less than 30. These are the suggested factors increasing the risk of Sharon becoming obese and diabetic. The second drug named "glycolistat" should work aiming at increasing the body's rate of metabolism and an increased rate of use of the ATP energy. This will ensure any excess glucose molecules are metabolized and the energy in form of ATP used. Its second mode of action should be interfering the body's ability in absorbing some nutrients in the daily diet. Most of the foods consumed by human beings contain some fats which increase the body weight and raising the Body Mass Index, therefore, when the drug’s mechanism of action is preventing absorption of the fats in the different kinds of foods, it will be therapeutically effective in decreasing Sharon’s weight and waist circumference(Fako, Zhang & Liu, 2014, pp 3444-3453). The last mechanism of this drug should be altering the patient’s appetite. When Sharon’s appetite is altered, she will tend to eat less than normal thus decreasing the number of calories she is consuming per day. Question 5 The Registered nurse standards for practice and the ICN code of ethics provides the nursing standards for practice. They clearly state that the registered nurse is accountable for his/ her decisions and actions such that when there is need to meet the client’s needs and the nurse
decides to delegate her duties to be undertaken by either, a nursing student or her fellow registered nurse, the nurse delegating retains accountability for the decision to delegate. The ICN code of ethics for Nurses has four elements that describe the standards of ethical conduct. From the first element which is the nurse and the people, we find that it describes the primary professional responsibility of a registered nurse to people is providing the nursing care to the people. In providing care the nurse will promote an environment in which Sharon's rights, her values, her spiritual beliefs, and cultural beliefs are respected. And therefore, any nursing actions that are against Sharon's beliefs will be avoided to preserve the boundary. The registered nurse will ensure that any medical or nursing information received by Sharon concerning her care is timely, accurate and is received in an appropriate manner culturally. The registered nurse will observe confidentiality when handling Sharon's information and medical records. And lastly, the nurse will be compassionate, respectful, responsive, and trustworthy while caring for Sharon. She should be in a position to demonstrate her professional values. Conclusion Type II diabetes mellitus is related to obesity and overweight.(Al-Goblan, Al-Alfi, &Khan 2014, p 587).Obesity is confirmed by measuring the waist circumference and calculating the Body Mass Index when given the Height and Weight of a person. A circumference of more than 88 cm indicates the client as obese and a BMI of over 30 is also a confirmation for obesity. When type II diabetes progresses with time it leads to kidney failure whereby it starts with kidney nephropathy that develops into kidney failure altering the kidney function (Alicic, Rooney, & Tuttle 2017, pp.2032-2045). Impaired kidney function can lead to hypertension. The registered nurse is therefore required to observe the code of ethics while providing care for the client. The ICN code of ethics has four elements. In the essay, the first element was discussed
which described what Sharon as the client should expect from a registered nurse caring for her condition.
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References. Al-Goblan, A.S., Al-Alfi, M.A. and Khan, M.Z., 2014. Mechanism linking diabetes mellitus and obesity.Diabetes, metabolic syndrome and obesity: targets and therapy,7, p.587. Alicic, R.Z., Rooney, M.T. and Tuttle, K.R., 2017. Diabetic kidney disease: challenges, progress, and possibilities.Clinical Journal of the American Society of Nephrology,12(12), pp.2032-2045. American Diabetes Association, 2017. 2. Classification and diagnosis of diabetes.Diabetes care,40(Supplement 1), pp. S11-S24 Ashwell, M. and Gibson, S., 2016. Waist-to-height ratio as an indicator of ‘early health risk’: simpler and more predictive than using a ‘matrix’based on BMI and waist circumference.BMJ open,6(3), p.e010159 Bae, J.P., Lage, M.J., Mo, D., Nelson, D.R. and Hoogwerf, B.J., 2016. Obesity and glycemic control in patients with diabetes mellitus: analysis of physician electronic health records in the US from 2009–2011.Journal of Diabetes and its Complications,30(2), pp.212-220 Fako, V.E., Zhang, J.T. and Liu, J.Y., 2014. Mechanism of orlistat hydrolysis by the thioesterase of human fatty acid synthase.ACS catalysis,4(10), pp.3444-3453. Foucquier, J. and Guedj, M., 2015. Analysis of drug combinations: current methodological landscape.Pharmacology research & perspectives,3(3), p.e00149. Hall, M.E., do Carmo, J.M., da Silva, A.A., Juncos, L.A., Wang, Z. and Hall, J.E., 2014. Obesity, hypertension, and chronic kidney disease.International journal of nephrology and renovascular disease,7, p.75.
Majumder, K. and Wu, J., 2015. Molecular targets of antihypertensive peptides: understanding the mechanisms of action based on the pathophysiology of hypertension.International Journal of Molecular Sciences,16(1), pp.256-283. Nankervis, A., McIntyre, H.D., Moses, R., Ross, G.P., Callaway, L., Porter, C. and Jeffries, W., 2014. ADIPS consensus guidelines for the testing and diagnosis of gestational diabetes mellitus in Australia.Modified June Prabhakar, P.K., Kumar, A. and Doble, M., 2014. Combination therapy: a new strategy to manage diabetes and its complications.Phytomedicine,21(2), pp.123-130. Reidy, K., Kang, H.M., Hostetter, T. and Susztak, K., 2014. Molecular mechanisms of diabetic kidney disease.The Journal of clinical investigation,124(6), pp.2333-2340