Impact of Sickle Cell Anemia on Family: Research Aims, Objectives, Methodology, and Literature Review

This paper aims to identify the impact of sickle cell anemia on the family of children between 0 to 16 years for better understanding and management of the disease. It includes research aims & objectives, background, research methodology, and literature review of six papers.

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Table of Contents
Table of Contents.......................................................................................................2
Introduction.................................................................................................................3
Research aims & objectives......................................................................................3
Background.................................................................................................................3
Research Methodology........................................................................................................3
Literature review....................................................................................................................4
Paper 1..................................................................................................................................4
Paper 2..................................................................................................................................4
Paper 3..................................................................................................................................4
Paper 4..................................................................................................................................4
Paper 5..................................................................................................................................4
Paper 6..................................................................................................................................4
Ethics........................................................................................................................................4
Conclusion..............................................................................................................................4
References..............................................................................................................................5
Appendices.............................................................................................................................5
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Introduction (300)
With the growing prevalence of chronic disease, sickle cell anemia is defined as one of most
common inherited disease in the United Kingdome. The clinical features of the sickle cell
anemia are severe pain which is the reoccurring ant and unpredictable in nature. One of the
most common features of the disease is that it has a huge impact on the quality of the life of
both patients and family members and careers. Sickle cell anemia has become an integrated
part of the health and social care practice since it influences the global burden of the disease.
The prime reason behind it is that Children with sickle cell anemia are at higher risk of
developing psychological diseases since. In addition, a frequent problem of pain, withdrawal
from the social interactions and abnormal social behavioral, different cognitive structures are
the common features of the sickle cell anemia which greatly impacted the quality of life in
the cell. Therefore, by integrating it in the health and social care practice able to provide an
opportunity to the community health workers in order to support the patient with sickle cell
anemia and family members who are experiencing negative events in life which decreases
the quality of life. The incorporation of family members and social caregiver in the health
practice proved to improve the effectiveness of clinical interventions and strengthen the
interpersonal relationship. The Aim of the paper is aimed to identify how Sickle Cell
Disease impacts on the Family to contribute to a better understanding and management of
the disease. This paper will illustrate Research aims & objectives, background, research
methodology and literature review of six paper in the following paragraphs.
Research aims & objectives (100)
The aim of the paper is to identify the impact of sickle cell anemia on the family of children
between 0 to 16 years for better understanding and management of the disease. The rationale
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behind this is although various medical interventions in the clinical research try to shape the
management of this increasing issue amongst children, identifying the impact amongst the
family would be helpful to integrate it in the health and social care practice in order to
support the family members.
The objective of the study:
• To identify the cause of sickle cell anemia in children between 0 to 16.
• To identify the impact of sickle cell anemia on the family of children between 0 to 16
years
• To recommend the ways by which it can be integrated and social practice for the
management of the disease.
Background (400)
A study suggested that sickle cell anemia is a condition where the glutamic acid of the blood
hemoglobin is converted to the valine amino acid due to the point mutation in the DNA.
Consequently, blood hemoglobin becomes distorted and blocks the vessels which in turn
give rise to sickle cell anemia. Due to distortion in shape, blood hemoglobin failed to carry
enough oxygen throughout the body. According to, amongst children and adult with the
sickle cell anemia with the median age at which death has occurred was 42 for male and 48
years for the females. Approximately, 12500 and 15000 individuals in the United Kingdom
are suffering from the sickle cell anemia and the prevalence of the disease is increasing
rapidly due to the frequent immigration into the Uk as well as a new birth.
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It is estimated that 1.47 percent of newborn babies in England are diagnosed with SCD as
they carry the sickle cell gene. The prevalence of the disease highlighted not only in a core
part of the united kingdom such as England but also urban areas of the United Kingdom.
Research Methodology (800)
Start with the confusions between methodology and methods
Provide definitions of both method & methodology
Discuss qualitative and quantitative methodology and state strengths and limitation (cite
your work)
State how methodologies are informed by philosophy and mention epistemology and
ontology – include a brief definition of both epistemology and ontology.
Discuss what your proposal draws on (i.e. the proposal utilises research based on both
methodologies – qualitative and quantitative) and seeks to achieve broader views and
perspectives (cite the mixed methodology paper on Moodle).
Research refers to a systematic way of finding about a field, a topic, or an experience.
Polit and Beck (2006) define research as a scientific way of solving questions or
problems. Hek& Moule (2006) are more elaborate in their definition of research and
view research as a systematic way of gathering information to answer research
questions to advance our knowledge of a field, a topic, or an experience.
To conduct research, researchers require research methodologies, and methods. Crotty
(1998) defines methodology as……. And methods as …….give examples of methods
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In health and social care research, two types of methodologies tend to be cited –
qualitative and quantitative methodologies.
Discuss advantages of qualitative methodology
Discuss how some or all the advantages of qualitative research inform your topic*
Discuss disadvantages of qualitative methodology
Discuss advantages of quantitative methodology
Discuss how some or all the advantages of quantitative research inform your topic*
Discuss disadvantages of quantitative methodology
Acknowledge and consider the existence of mixed methodology or design
Discuss how your research can benefit from the use of both qualitative and
quantitative methodologies
Underpinning research methodologies and methods are philosophical assumptions
about reality and knowledge and how they may be acquired. These assumptions
include research paradigms, defined by Guba & Lincoln (1994, p.105) as “basic belief
system or world view that guides the investigation” they also include ontology – the
theoretical position researchers adopt in finding about their study. For example,
Feminist ontology – describe….
The field of X draws from both positivist and constructivist ontology - discuss
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If the ontology underpinning your field/topic is not clear, or is informed by both
positivist and constructivist, state this in your discussion. Please reference your six
papers to back this argument.
The philosophical assumption also touches on epistemology which itself poses three key
questions: what is knowledge made up of? How do we acquire it? What relationship (s)
should researchers have with their research participants? Different types of
epistemologies are cited in health and social care research and some are more
appropriate in some research contexts more than others. For example, positivist
epistemologies posit that knowledge is discovered and verified through facts and
experiments. The researcher is viewed as an outsider – meaning he/she does not see
themselves as an active part of the research process. This is so to maintain objectivity
and avoid biases. This epistemology informs quantitative methodologies….[state how
this epistemology may fit with your topic].
By contrast, constructivist epistemologies….
Positivist epistemologies are sometimes contrasted with naturalist or constructivist
epistemologies which hold that knowledge is established through the meanings which
people attach to their experiences. In this regard, the researcher adopts an insider role
and interacts with participants to gain deeper insights into their lived experiences (Coll
& Chapman, 2000). Although subjective by nature, this epistemology underpins the
traditions of qualitative research, ….[state how this epistemology may fit with your
topic].
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Literature review (500)
Provide a definition of literature review
Introduce the reader to the types of literature review (i.e. systematic and narrative
literature reviews)
Introduce evidence based practice (EBP) what is it?
Describe its uses in Health and Social Care contexts
Describe its importance
Discuss your chosen papers are identified (i.e. did you use inclusion and exclusion
criteria?)
Say something about how you identified your papers
Using Discover@ Bolton
Used search terms
Inclusion and exclusion criteria
Mention how you utilise the CASP Chart to ensure relevance, resonance, and
credibility of your literature review strategy (i.e. CASP was used to review literature).
Add a table in the appendix to evidence this.
Introduce the papers you want to review here (i.e. based on the CASP literature
review, the following section discusses the six papers chosen for this proposal which are
also presented in Appendix x.
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(1500)
Paper 1
Provide an overview of the paper – be fair but critical (identify strengths and
limitations)
Begin with describing what the paper entails
Aims and Objectives
Methodology and methods
Findings
Limitations
Paper 2
Paper 3
Paper 4
Paper 5
Paper 6
Ethics (250)
What is ethics?
Describe ethics – state what it involves
Sate the University Ethics Procedure – include ethics form in the appendix
Explain why it is important in your topic (consider sensitivity of some topics; i.e. suicide,
violence, bullying, etc.)
Conclusion (250)
Pull your discussion together
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End with stating the importance of proposal (i.e. the proposal reviewed a wide range of
literature, and brought forth important discussion on topic X. More specifically, the proposal
adds useful dimension of the topic, and provides evidence for policy makers, as well as
important direction for further research on topic x.
References
All references used in the proposal
Arrange references in Alphabetical order
Appendices
CASP Chart List
Other appendices you stated in the proposal.
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