PH7013 Dissertation: A Systematic Review on Prostate Cancer Management

This document presents a student's systematic review form focusing on prostate cancer. It explores the concept, pathophysiology, causes, and risk factors associated with the disease. The review also investigates interventions aimed at reducing the risk of prostate cancer, utilizing the PICO framework to define the problem, intervention, comparison, and outcome. The project confirms it does not involve direct human participants, and it identifies the work as a systematic review with original and well-defined questions. The description of the project provides an overview of prostate cancer, its development, symptoms, and potential complications, as well as treatment options. The student confirms that the project is not research and does not require ethical or scientific merit review.

Student Systematic Review Form
This form should be used if the applicant and supervisor have concluded that a project is a
systematic review and does not require ethical or scientific merit
Section 1: Applicant Details
Applicant Name:
Student number:
Programme of
study:
Correspondence
Address:
Email address:
Please Tick 
I confirm that this is a student project for a PGR academic award.
Section 2: Supervisor Details
Name of Supervisor:
Email Address:
Section 3: Systematic Review Details
Title of systematic review or review of literature (please give full title):
 What are the concept and pathophysiology of prostate cancer?
In this, the basic concept of the prostate cancer is discussed with the pathophysiological aspect which
provide additional support to understand the knowledge regards with prostate cancer.
 What are the causes and risk factor of prostate cancer?
The major causes and risk factor is discussed which may create critical issue and problem with prostate
cancer.
 What are the ways/intervention to reduce the risk of prostate cancer?
In this, the pharmacological intervention such as medication, therapy and other drug regimen are
introduced with proper diagnostic and performed management for prostate cancer.
PICO framework
P-problem: The identified problem is prostate cancer.
I-intervention: Proper medication, management and self-management.
C-comparison: Other drug regimen and combination effect of drugs.
O-outcome: Improve healthy behaviour and reduce cases of prostate cancer.
Question Yes No If Yes please provide further detail
Does the project involve human
participants, either directly (e.g. through No
1

use of interviews, questionnaires)
Or indirectly (e.g. through provision of,
or access to, a person’s data). No
If you have answered Yes to either the above questions, then it is likely that you will need to
complete the ethics application form available at:
https://portal1.chester.ac.uk/fhsc/Pages/accessing-the-application-forms.aspx
Please complete the following if you have answered No to the previous two questions:
Question Yes No If Yes please provide further detail
Does the title identify the work as a
systematic review or review of the
literature, or both?
Yes They have proper title in which
investigation is being taken in order to
collect more information.
Is the question posed original and well
defined?
Yes The question is appropriate which help
to extract information through this
research questions.
Will the work affect the confidentiality
originally promised to study participants?
No
Will you be contacting the original
researchers for more information?
No
Description of Project (250 words)
Prostate cancer is defined as the cancer which occurs in the prostrate. As per this, the prostrate is a
small shaped gland in males help to produce the seminal fluid that help to nourish and used to
transport the sperm. In this, the Prostrate cancer is most common type of cancer which is grow slowly
and are confined to the Prostate gland. However, in some of the cases of cancer they do no required
any treatment and for other type they can grow aggressively which can spread quickly. This cancer is
detected in early stage which is treatable in successful manner. The prostate cancer has no any sign
and symptoms during their early stage. As per this, when the condition become more critical at their
advance stage they include trouble in urinating, decreased force in the stream of urine, blood in the
urine, blood in the semen and bone pain. In addition to this, there is no any proper cause of prostate
cancer in which cancer is begin when cell in the prostate develop change in their DNA. Moreover, cell
usually contain DNA which change their growth and divide more normal cell, abnormal cell continues
living when other cell is die. This accumulation of abnormal cell forms a tumour that can grow
rapidly and create the complication. Some of the abnormal cell used to break and show the
metastasize phase in other body part. In this, the major complication which is associated with the
prostate cancer is cancer can be spread, incontinence and erectile dysfunction and many more. They
have proper treatment after the diagnosis which can be retaliated by using proper therapy and drug
regimens.
2

Section 4: Declarations & Signatures Please Tick  
We confirm that we have reviewed the project protocol and checked
http://www.hra.nhs.uk/documents/2016/06/defining-research.pdf to define the project
category.
We conclude that the project is not research and does not require ethical or scientific merit
review.
Signatures
Applicant: Date:
Supervisor (student) or
Line Manager (staff): Date:
Section 5: Declaration of Governance Please Tick  
I confirm that the application has been through due process.
Signed:
Chair of the Faculty Research Committee Date:
For Admin Use Only
Date Recorded: Date of FRC Meeting:
3