Ramipril: Mechanism, Indication, and Adverse Effects

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Indication:
 This drug is used for treatment
of hypertension for lowering the
blood pressure
 It helps in the prevention of
stroke, heart attack, kidney
problems
 Medication should be taken by
mouth once or twice daily with
or without food (Wahba et al.
2015)
 Daily dosage should be 2.5-20
mg a day as a single dose or two
divided doses
Drug class:
 This medication belong to the
category of angiotensin
converting enzyme inhibitor
 This category inhibits ACE and
this prevents action of the
angiotensin II activity
 angiotensin II participates in
contracting the muscles around
the blood vessels increasing the
pressure within the blood
vessels, this increases the blood
pressure (Soares et al. 2018)
 ACE inhibitors reduces the
concentration of the angiotensin
II, so blood vessels dilate and
blood pressure gets reduced
General mechanism
 The medication inhibit the
production of the angiotensin
converting enzyme