Translational and Quantitative Research Approaches

This document provides an overview of translational research and quantitative research approaches. It discusses the goals, data collection methods, and differences between these two types of research. The document also includes references for further reading.

Task
Research practice
Translational and quantitative research approaches
University
Name
Tutor
Date

Translational Research Graphic Organizer
Type Translational
Research
Quantitative
Research
Observations
(Similarities/Differences)
Methodology T1- Translation to
Human research
- It relates to the
development of treatments
and interventions
T2- Translation to
patients research
- It relates to testing of
effectiveness and efficacy of
treatments and interventions
T3-Translation to
Practice research
- It relates to
dissemination and
implementation of system-
wide changes of research.
(Pomeroy & Sanfilippo,
2015)
Quantitative methods
emphasize the
objective assessments
and the inherent
statistical,
mathematical and
numeral analysis of
data through collection
using various methods
such as polls,
questionnaires,
surveys and
manipulation of pre-
existing data through
the usage of
computational
approaches.
It focuses on
numerical data and
generalization across
the population to
elaborate on a specific
phenomenon.
(Bell, Bryman &
Harley, 2015)
- The inherent difference
on these two types of
research entails that
translation research
seeks to use an already
available set of evidence
or data while in
quantitative research
type, it seeks to develop
and come up with data
which can be used to
generate a concept to be
used in clinical settings.
Goals T1- Translation to
Human research
- The inherent
interface existing between
the basic and clinical setting
research seeks to find how
new knowledge of disease
The goal of
quantitative research is
to establish a
relationship between
the dependent and
independent variable
within a set of
- There are inherent
differences between
these two types of
research.
Translational seeks
to apply newly
found knowledge

can be enhanced into clinical
practices and key diagnostic
and treatments phases in
human trials.
T2- Translation to
patients research
- The goal revolves
around the application of
newly found information
into insights obtained from
clinical and population
research settings towards
health service provision.
T3-Translation to
Practice research
- The research aims at
disseminating and
implementing system-wide
changes.
- The key goal of
translation to practice
research entails on moving
evidence-based guidelines
entrenching into health
practice through
dissemination and research
diffusion.
(Zoellner & Kathleen,
2017)
population. Designs
utilize in quantitative
research designs are
descriptive or
experimental.
Descriptive research
focuses on
establishing an
association between
variables while the
experimental type
assesses the causality
of a problem.
(Creswell & Creswell,
2017)
and practice into the
health care arena,
while quantitative
approach seeks to
assess the
relationship between
the dependent and
independent
approaches of
research.
- Further, on
translational to
practice research
seeks to disseminate
already synthesized
knowledge into
practices through
evidence-based
practice, while
quantitative
approaches are far
from this stage.
Data
Collection
T1- Translation to
Human research
- This research is an
interface between the normal
research and general health
care setting, leading to
finding new knowledge of
Quantitative data
collection methods
revolve around
random sampling and
structured data
collection avenues
which fit into diverse
and predetermine
- There are wide
differences between
these two
approaches, the
translational
research focuses on
implementing a
proven practice and

disease mechanisms and how
it can be entrenched into
health care practices and
regimes needed to be tried in
humans.
- Types of
methodological approaches
being adopted in this type
entail, observational studies,
case study assessment, phase
1 and 2 trials.
T2- Translation to
patients research
- This entails
application of information
obtained from basic, clinical
and across the population
towards health care
practices.
T3-Translation to
Practice research
- It involves the use of
evidence from clinical trials
on careful selection of
patients translated is not
guidelines for complex
patients observed in clinical
practices.
- Types of
methodological approaches
used in this study entail
aspects used in
dissemination research,
implementation research,
and diffusion research and
phase IV clinical trials.
(Khodyakov et al.,
responses. This
produces results which
are easy to summarize,
make comparison and
offer generalization.
Quantitative
approaches entails
testing hypothesis
which is derived from
theory and estimating
the size of the
phenomenon of key
interests. Participants
in the study can be
assigned to different
treatment protocols.
(Bryman, 2017)
entrenching into
health care practices
leading to the
establishment of
new disease
mechanism control.
- Quantitative
approaches seek to
collect data based on
various
methodological
approaches used to
obtain primary data,
which are essential
in interpreting and
establish the
relationships
between dependent
and independent
variables in the
study, thereafter a
proposition is made
based on findings
obtained.

2016)
References
Bell, E., Bryman, A., & Harley, B. (2018). Business research methods. Oxford university press.
Bryman, A. (2017). Quantitative and qualitative research: further reflections on their integration. In
Mixing methods: Qualitative and quantitative research (pp. 57-78). Routledge.
Creswell, J. W., & Creswell, J. D. (2017). Research design: Qualitative, quantitative, and mixed
methods approaches. Sage publications.
Khodyakov, D., Mikesell, L., Schraiber, R., Booth, M., & Bromley, E. (2016). On using ethical
principles of community-engaged research in translational science. Translational Research,
171, 52-62.
Pomeroy, C., & Sanfilippo, F. (2015). How Research Can and Should Inform Public Policy. In The
Transformation of Academic Health Centers (pp. 179-191). Academic Press.
Zoellner, J. M., & Porter, K. J. (2017). Translational Research: Concepts and Methods in Dissemination
and Implementation Research. In Nutrition in the Prevention and Treatment of Disease (pp.
125-143). Academic Press.