6-Fill in the following table of donor-recipient compatibility in the ABO blood group system, using ticks and crosses to indicate compatibility and non-compatibility, respectively, for a donation of one or two units of whole blood. DONOR0ABABRECIPIENTOABAB7-Explain why some transfusions are safe one way round but if the same donor-recipient pair are reversed (i.e. donor becomes recipient and vice-versa) there is likely to be an agglutination reaction. (5 lines)Many have RH factor on the surface of red blood cells. Those who have this antigen are called Rh+ and those without are Rh-. Rh- people do not have rhesus antibodies naturally in their blood plasma. When a Rh+ receives blood from a Rh- there is no agglutination but when a Rh- receives blood from a Rh+ agglutination occurs because rhesus antigen can trigger production of rhesus antibodies in the person with Rh- blood.8-What happens if you transfuse a large volume of blood from a compatible donor (according to the previous table), but with a different blood type? (4 lines)There is no antigen-antibody reaction that will occur hence there is no transfusion reaction islikely to occur but transfusing large volume of fluid may lead to fluid overload which may result to pulmonary oedema and acute respiratory failure. 9-Use this principle to predict whether blood donors who are positive for Rhesus factor (D-antigen) cab donate small quantities (10r 2 units) of whole blood to Rhesus negative recipients or vice-versa. (8 /10 lines) Rh positive person can donate to the Rh negative blood person only if it is for the first time. Since Rh- blood person does not have Rh antibodies naturally in their blood plasma there is likely to be no immediate danger. But on subsequent transfusion there will be severe transfusion reaction as the Rh- individual has been initial exposed to the Rh antigen and has developed antibodies against it hence agglutination will occur. A Rh- individual can donate toboth the Rh+ individual or Rh- individual without any adverse transfusion reaction occurring.This is because there is no antigen antibody reaction against the Rh antigen.10-Draw a chart to illustrate the titre (relative concentration) of specific antibodies in the blood of a patient who has been challenged with a microorganism once, and then again with the same organism at a later date.

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