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The Liver and Its Enzymes in Pathology : Assignment

   

Added on  2020-07-22

6 Pages1320 Words67 Views
Disease and Disorders
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THE LIVER AND ITS ENZYMES INPATHOLOGY
The Liver and Its Enzymes in Pathology : Assignment_1

Table of ContentsINTRODUCTION...........................................................................................................................1TASK ..............................................................................................................................................11........................................................................................................................................................12........................................................................................................................................................13........................................................................................................................................................2PART 2 ...........................................................................................................................................2CONCLUSION ...............................................................................................................................3REFERENCES ...............................................................................................................................4
The Liver and Its Enzymes in Pathology : Assignment_2

INTRODUCTIONLiver is very important organ of the human body and functioning of liver can be greatlyimpaired in various conditions. It is essential that functioning of liver should be maintained sothat smooth functioning of human body should be ensured.TASK 1There are 3 different patients naming Mr X, Y and Z. They all are exhibiting symptomsthat are associated with the liver damage. Blood and urine samples of this type of patients istaken so that necessary medical analysis should be performed. Mr X is alcoholic and when anindividual consumer alcohol than chronic exposure towards alcohol lead towards activatingHepatic Macrophages which is a third site of metabolism (Sebrell, and Harris,eds., 2014). Itproduces TNF-ALPHA and it induces reactive oxygen species in the body tissue mitochondria.People who regularly consumes Alcohol are having deficiency of antioxidants and it includesVitamin E and Glutathione (Liver. 2017.). These type of patients are subjected towards hepatocyte necrosis and stress levelpromotes apoptosis in this type of patients. Lipid peroxidation is also induced among thesepatients and it causes fibrosis and inflammation. Alcoholic patients are more prone towards liverdamage and due to this they face issues such as liver damage. Free radicals that are produced inthis process creates lipid peroxidation. In the whole process when cellular proteins are boundtogether with the metabolic acetaldehyde than due to that antigenic adducts are produced. Itcreates and induces inflation in the body and due to that functioning of intestinal mucosa isaffected. It aid for production of endotoxaemia and hepatic inflammation is created in thepatients. 2Mr Y is suffering from obesity and it is the cause behind liver damage. Alcoholic liverdisease are major cause that lead towards creating fibrosis and cirrhosis. Due to obesitymalfunctioning of liver occurs and metabolic dysfunctionality occurs in the individual (Zachary,and McGavin, 2013). Organ dysfunctionality also occurs and cardiac, intestinal, insulin resistantand anti inflammatory diseases are caused due to this. Due to obesity immune dysfunctions also1
The Liver and Its Enzymes in Pathology : Assignment_3

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