Therapeutics in Nursing

Running Head: Therapeutics in Nursing
THERAPEUTICS IN NURSING

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Therapeutics in Nursing
Table of Contents
1. Reviewing Jame’s medication chart.......................................................................................3
2. Mechanism of action of medications...................................................................................10
Reference list............................................................................................................................15

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Therapeutics in Nursing
1. Reviewing Jame’s medication chart
Name of medicine
Aspirin
Use
Used to treat chest pain, reduce fever and prevent heart attacks or strokes.
Side effect
Stomach ache, discomfort, bloody urine, drowsiness, fast breathing
Interaction
Several drug interactions including warfarin, may increase weakness and vomiting.
Acetazolamide can increase nausea and vomiting1. Other medicines like ramipril have
moderate interactions. Moreover, oral hypoglycemic agents increase hypoglycemic activity
of aspirin. In addition, garlic, ginger may increase the risk of bleeding.
Nursing implication
The medicine needs to be applied in perfect dose as prescribed by the doctor. Regular
monitoring regarding tolerance of aspirin is essential. Different side effects like vomiting,
nausea needs to be measured2. Other behavioral changes like drowsiness, lethargy, and
constipation must be monitored to control the dosage of the patient.
1 Dai, G., Jiang, Z., Bai, Y., Zhang, Q., Zhu, L., Bai, X., ... & Pan, R. (2017). Pharmacokinetic herb–drug
interaction of Xuesaitong dispersible tablet and aspirin after oral administration in blood stasis model
rats. Phytomedicine, 26, 62-68. Retrieved from:
https://www.sciencedirect.com/science/article/pii/S0944711317300260
2 Woessner, K. M. (2015). Aspirin desensitization for cardiovascular disease. Current opinion in allergy and
clinical immunology, 15(4), 314-322. Retrieved from:
https://journals.lww.com/co-allergy/Fulltext/2015/08000/Aspirin_desensitization_for_cardiovascular_disease.8.
aspx

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Therapeutics in Nursing
Name of medicine
Metformin XR
Use
Used to reduce production of glucose by liver, glucose amount that body absorbs and
enhance the effect of insulin on body.
Side effect
Diarrhea, stomach pain, gas, heartburn, and nausea
Interaction
Use of carbonic Anhydrase inhibitors (for example, Methazolamide, Brinzolamide,
Acetazolamide, and others) with Metformin XR may enhance the risk of lactic acidosis.
Drugs that affect common renal tubular transport systems such as cimetidine, ranolazine, and
others, if consumed with Metformin XR, may enhance the chance of occurring lactic
acidosis3. Insulin can increase the risk of hypoglycemia and alcohol has a great influence on
the effect of this drug in case of lactate metabolism.
Nursing implication
Test of liver and kidney function must be done. Nurses need to monitor alcohol
consumption by patients and cardiopulmonary status4. Level of lactic acidosis must be
measured. Based on doctor’s advice, dosage must be determined.
Name of medicine
Ramipril
Use
3 Accessdata.fda.gov. GLUCOPHAGE® XR. Retrieved on 28th August 2019, from:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020357s031,021202s016lbl.pdf
4 Healthline.com. (2019) Metformin, Oral Tablet
Contents. Retrieved on 28th August 2019, from: https://www.healthline.com/health/metformin-oral-tablet