Assignment on Hepatitis C Virus

University of Rajshahi
Department of Pharmacy
Course: Pharmaceutical Microbiology and Immunology(107)
Assignment on Hepatitis C Virus
MD. S. M. SHAKIB
Roll: 2011126102
Address: B. Pharm(Part-I)
E-mail :
[e-mail]
Submitted by
DR. MD. AJIJUR RAHMAN
Associate Professor
Department of Pharmacy
University of Rajshahi
Email: [e-mail]
Submitted to
Date of submission: October 20,2020

The hepatitis C Virus (HCB) is small,
enveloped, positive-sense single stranded RNA
virus of the family Flaviviridae. The hepatitis C
virus is the cause of hepatitis C and some
cancers such as liver cancer ( hepatocellular
carcinoma, abbreviate HCC) and lymphomas in
human.
Hepatitis C Virus

Unranked: Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Kitrinoviricota
Class: Flasuviricetes
Order: Amarillovirales
Family: Flaviviridae
Genus: Hepacivirus
Species: Hepacivirus C
Classification

√ The hepatitis C virus particle consists of a
lipid membrane envelope that is 55 to 65 nm in
diameter. Two viral envelope glycoproteins E1
and E2 are embedded in the lipid envelope.
√ They take part in viral attachment and entry
into the cell. Within the envelope is an
icosahedral core that is 33 to 40 nm in
diameter. Inside the core is the RNA material of
the virus.
√ E1 and E2 are covalently bonded when
embedded in the envelope of HCV and are
stabilised by disulfide bonds.
S t r u c t u r e