This nursing report addresses the clinical practice issue of stimulant use for academic performance enhancement, focusing on a PICO question: "Do stimulants increase academic performance in university students?" The report evaluates two studies: a qualitative study by Hildt et al. (2014) examining the contextual factors of stimulant use, and a quantitative study by Munro et al. (2017) investigating the relationship between nonmedical use of prescription stimulants, executive functioning, and academic outcomes. The report utilizes the PICO model to formulate the clinical question and discusses barriers to implementing evidence-based practice, such as the complexity of research, lack of access to resources, and potential risks associated with stimulant use. The findings suggest that stimulants can increase academic performance, but non-medical use may be harmful.