This report provides a systematic review of the adverse health effects associated with particulate matter (PM) and other air pollutants. It begins with an introduction highlighting the global concern of air pollution and its link to premature deaths caused by diseases like strokes, heart attacks, and respiratory illnesses. The report then details the PICO question and search strategy used to find relevant articles from databases such as CINAHL, ScienceDirect, and PubMed. Inclusion and exclusion criteria are clearly defined, focusing on cohort and observational studies published after 2016. The study results section summarizes findings from five selected articles, each exploring the relationship between air pollution and specific health outcomes, including atrial fibrillation, mortality, diabetes, and myocardial infarction. Biological plausibility is discussed, citing research that explains how PM exposure can lead to respiratory and cardiovascular diseases. The report concludes by emphasizing the critical need for global efforts to reduce air pollution and protect human health, suggesting future research on the effectiveness of control measures for different air pollutants. The report includes a comprehensive list of references supporting the research findings.