Report on Alzheimer's Disease: Causes, Effects, and Treatment

This report provides a comprehensive overview of Alzheimer's disease, aiming to enhance understanding of its causes and impacts. It begins with an introduction outlining the report's objectives and scope, followed by a literature review that analyzes four key sources. These sources explore the genetic risk factors associated with Alzheimer's, the effects of the disease on patients and their families, the economic costs, and the strategies employed by the NHS to address the issue. The report contrasts and compares these sources, highlighting the multifaceted challenges posed by Alzheimer's disease. The conclusion synthesizes the findings, emphasizing the disease's detrimental effects on individuals and families, while also acknowledging the role of healthcare systems in providing treatment and support. The report underscores the need for awareness and proactive measures to mitigate the impact of Alzheimer's disease on individuals and society. The report's references include various books and journals that provide a deeper understanding of the disease.

Problem based report

Table of Contents
1. INTRODUCTION.......................................................................................................................1
1.1 Report aim.............................................................................................................................1
1.2 Topic area..............................................................................................................................1
2. Literature review..........................................................................................................................1
2.1 Source 1 (Genetic risk for Alzheimer disease in distinct from genetic risk for amyloid
deposition)...................................................................................................................................1
2.2 Source 2 (Effect of Alzheimer disease on Patients and their family)...................................2
2.3 Source 3 (Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of
iceberg').......................................................................................................................................2
2.4 Source 4 (Dementia in the UK: Preparing the NHS for new treatment)...............................2
2.5 Contrast and comparison.......................................................................................................3
3. CONCLUSION............................................................................................................................3
REFERENCES................................................................................................................................4

1. INTRODUCTION
1.1 Report aim
The report main aim is to provide the deep understanding of the Alzheimer disease which
sometime may cause death . Through this report, researcher select four different sources related
to the topic which assist to determine whether Alzheimer actually create negative cause to a
human body or not.
1.2 Topic area
Background: Alzheimer is that disease which cause brain cells to degenerate and die.
This disease is the most common cause of dementia and as a result, it also lead to continuous
decline in thinking and social skills which further disrupt person's ability to function
independently.
Rationale: The reason of choosing this specific topic is such that Alzheimer is one of the
most leading cause of death after heart disease in 2018 i.e. in England there were more than 5 lac
deaths were registered in England and Wales during last year. Therefore, by study on this
particular topic will assist to enhance the knowledge with regards to topic and provide remedies
to cope up with this disease.
Through this study, researcher find out the main cause of Alzheimer among people and
different challenges which are face by people while they are suffering from Alzheimer.
Moreover, the result and conclusion generated from the study will also assist to determine the
causes of increases deaths due to Alzheimer disease and its affect upon the public health in UK.
2. Literature review
Literature review is the scholarly paper which provide an overview of current knowledge
and also allow to identify the relevant theories and gaps in their existing research. Further,
through this section, researcher collect different articles, books and journals which also allow
researcher to determine the nature and determine the gap as well.
2.1 Source 1 (Genetic risk for Alzheimer disease in distinct from genetic risk for amyloid
deposition)
This study main objective is to determine the factor which are responsible for a huge and
growing health care burden in developing world. Further, in the study, researcher uses Polygenic
risk score approach which has shown 75 to 84% prediction accuracy to determine Alzheimer
disease among an individual (Leonenko and et.al., 2019). From the study, it is also concluded
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that Apolipoprotien is involved in the metabolism of a fats within a body that actually increase
the chances of Alzheimer disease among individuals. Moreover, this source helps to determine
genetic risk factor that actually lead to increase the chance of Alzheimer among people.
2.2 Source 2 (Effect of Alzheimer disease on Patients and their family)
The study conduct by Grabher (2018) examine the epidemic Alzheimer disease create
impact upon patient and their family member in the term of emotional, psychological and
financial terms. The results interprets that only caregiver can reduce the stress and also balance
the family responsibilities so that they can cope up with this disease. Further, research study
also suggest there are many ways through the Alzheimer may reduce and an individual may live
their own life in better way. This source is also related to the study because it will help to
determine how caregivers and different hospitals support the person who suffer from this study.
2.3 Source 3 (Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of
iceberg')
This article highlight the hidden cost of Alzheimer's such that people also develop other
health condition i.e. anxiety and depression , family forced to cut back on spending and also use
their savings, also, reduce the quality of life for people. Further, in UK, this disease cost around
£26bn in a year that also lead to affect the overall social environment of a country (El-Hayek
and et.al., 2019). Sometimes, this cost also leads to develop many health issue such that
depression, anxiety and hypertension that further increase the cost and as a result, it creates
negative impact upon the society and families. This, study also assist to determine the
challenges from which families and society are suffer while dealing with Alzheimer's disease.
2.4 Source 4 (Dementia in the UK: Preparing the NHS for new treatment)
This article, helps to determine the strategies and steps used by NHS in order to reduce
Alzheimer' disease in UK, because there are more than 85 thousand people who are suffering
from this disease (The, 2018). The result of the study shows that NHS made risk factor
management and preventive strategies so that it will help to minimize the issue of Alzheimer
among people. The trust also develop different infrastructure who provide immediate response
to the patients. This article help to determine the steps taken by NHS in order to reduce the death
of people in UK and it will also assist to provide a healthy life to people as well.
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2.5 Contrast and comparison
From the above four sources, it is analyzed that the articles provide different challenges
which are face by people when they are suffering from Alzheimer disease. Such that first source
provide genetic factor that lead to disease, while, second source determine the effect of
Alzheimer's disease upon family and patients. On the other hand, third source provide economic
cost needed to treat an individual, while last source describe the strategies implemented by NHS
to deal with the issue. It is clear that all the four articles main motive is to ascertain that
Alzheimer is consider the second leading cause of death and there is a need to create awareness
among people to deal with a disease and examine the impact upon society as well.
3. CONCLUSION
By summing up above report it has been concluded that Alzheimer disease lead to cause
dementia and also affect the individual as well their family life. The study also concluded that
Alzheimer disease cause negative impact upon patient and their family's life and it did not only
affect the physical health of an individual but also cause emotional, psychological and financial
issues as well. Further, study also concluded that NHS also provide range of treatment facilities
to the individual so that they will contribute their small portion to the welfare of public.
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REFERENCES
Books and Journals
El-Hayek, Y. H. and et.al., 2019. Tip of the iceberg: assessing the global socioeconomic costs of
Alzheimer’s disease and related dementias and strategic implications for
stakeholders. Journal of Alzheimer's Disease, (Preprint), pp.1-19.
Grabher, B. J., 2018. Effects of Alzheimer disease on patients and their family. Journal of
nuclear medicine technology.46(4). pp.335-340.
Leonenko, G. and et.al., 2019. Genetic risk for alzheimer disease is distinct from genetic risk for
amyloid deposition. Annals of neurology.86(3). pp.427-435.
The, L., 2018. Dementia in the UK: preparing the NHS for new treatments. Lancet (London,
England).391(10127). p.1237.
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