This report provides a detailed overview of Alzheimer's disease (AD), a common neurodegenerative disorder. It explores the disease's characteristics, including neuropsychiatric symptoms and cognitive deficits. The report delves into the pathophysiology of AD, focusing on the accumulation of beta-amyloid plaques and neurofibrillary tangles composed of tau protein. It discusses the toxic effects of beta-amyloid and the role of tau in neuronal damage. The report also covers diagnostic methods, including clinical assessments, the use of biomarkers, and neuroimaging techniques such as PiB PET and MRI. The importance of timely diagnosis for effective disease management is emphasized. The report also highlights the challenges in diagnosing AD and presents various diagnostic approaches, including the use of computer-aided diagnosis (CAD). The report concludes by emphasizing the need for public and healthcare professional awareness of AD.
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