Detailed Analysis of Homo sapiens MLXIPL mRNA Sequence NM_032951

This document provides a detailed analysis of the Homo sapiens MLX interacting protein like (MLXIPL) mRNA sequence, specifically transcript variant 1 (NM_032951). The sequence, which is 3252 bp long, encodes a basic helix-loop-helix leucine zipper transcription factor involved in glucose-dependent activation of carbohydrate response element (ChoRE) motifs. The analysis includes information on the gene's structure, its role in triglyceride synthesis, and its association with Williams-Beuren syndrome. The document references multiple research articles that explore the function and regulation of MLXIPL, also known as CHREBP, in various cellular processes and diseases, including diabetic nephropathy and intervertebral disc degeneration. The data incorporates annotations on coding regions, exons, regulatory elements, and protein features such as phosphorylation sites and disordered regions, offering a comprehensive overview of the MLXIPL gene and its mRNA transcript.