Anti-fungal Drugs and Dental Care: Medications and Treatment Options

This report provides an overview of anti-fungal drugs and their relationship to dental care. It lists several anti-fungal medications, including Nystatin, Clotrimazole, and Fluconazole, and discusses their potential side effects such as mouth irritation, vomiting, and bad breath. The report also covers treatment interventions for managing these side effects, such as brushing, using alternative medications, and regular dental visits. Additionally, the report references several studies and research papers to support the information presented.

ANTI-FUNGAL DRUGS AND
DENTAL CARE

LIST OF ANTI FUNGAL DRUGS:
 Nystatin (mycostatin)
 Clotrimazole troches
 Fluconazole
 Ciclopirox
 Olamine
 Iitraconazole (Tripathi, 2016).

EFFECTS OF THE DRUGS/ DENTAL TREATMENT
 Nystatin (mycostatin); causes mouth irritation, diarrhoea and rashes (Scheibler et al., 2017).
 Clotrimazole troches: unpleasant sensation inside the mouth, vomiting, itching and stomach upset
(Vojdani et al., 2019).
 Fluconazole: unpleasant breath odour, hive like swelling of tongue, and lips.
 Ciclopirox: sever heath difficulties, as mentioned not to apply in the mouth.
 Olamine: rashes and burns inside the mouth, and diarrhoea.
 Iitraconazole. Vomiting, dizziness and swelling as well as bad breath (Dagli et al., 2015).
 As the effect of dental treatment, the associated sign and symptoms of the fungal infection can be
cured. However, it might cause some side effects which can be managed by the effective medication

INTERVENTIONS FOR SIDE EFFECTS OF THE MEDICATIONS:
 Brushing two times a day in order to avoid massive side effects.
 Using alternative medications when the condition getting worse (Kraft et al., 2015).
 Using mouth cleaning solutions.
 Routine visits to the dental care services (Bueno et al., 2015).

REFERENCE:
Bueno, M. G., Urban, V. M., Barberio, G. S., da Silva, W. J., Porto, V. C., Pinto, L., & Neppelenbroek, K. H.
(2015). Effect of antimicrobial agents incorporated into resilient denture relines on the Candida albicans
biofilm. Oral diseases, 21(1), 57- 65.
Dagli, N., Dagli, R., Mahmoud, R. S., & Baroudi, K. (2015). Essential oils, their therapeutic properties, and
implication in dentistry: A review. Journal of International Society of Preventive & Community Dentistry, 5(5),
335.
Kraft-Bodi, E., Jørgensen, M. R., Keller, M. K., Kragelund, C., & Twetman, S. (2015). Effect of probiotic
bacteria on oral Candida in frail elderly. Journal of dental research, 94(9_suppl), 181S-186S.
Tripathi, K. D. (2016). Antifungal drugs. In Essentials of Pharmacology for Dentistry (pp. 442-449). jaypee.
Scheibler, E., Garcia, M. C. R., Medina da Silva, R., Figueiredo, M. A., Salum, F. G., & Cherubini, K. (2017). Use
of nystatin and chlorhexidine in oral medicine: Properties, indications and pitfalls with focus on geriatric
patients. Gerodontology, 34(3), 291-298.
Vojdani, M., Zibaei, M., Khaledi, A. A. R., Zomorodian, K., Ranjbar, M. A., & Boshehri, S. (2019). In-vitro study
of the effect of clotrimazole incorporation into silicone soft liner on fungal colonization. Journal of
Dentistry, 9(Supplement 2009), 19-23.