This essay delves into the concept of selective toxicity in cancer treatment, a method that aims to target and eliminate cancerous cells while minimizing harm to healthy cells. It begins by defining selective toxicity and explaining how drugs, such as antimetabolites and alkylating agents, work to disrupt the growth and proliferation of cancer cells. The essay then focuses on chemotherapy, a widely used treatment, and explores its limitations, including significant side effects like nausea, weakened immune systems, and the potential for drug resistance. It examines specific drugs like cyclophosphamide and paclitaxel, highlighting their mechanisms of action and associated drawbacks. Furthermore, the essay discusses other cancer treatment methods, such as surgery, hormone therapy, immunotherapy, and radiation therapy, while also exploring the efficacy of combination therapies and the importance of personalized medicine in addressing the heterogeneous nature of cancer. The essay concludes by emphasizing the ongoing efforts to develop more effective and targeted anticancer agents and acknowledging the challenges that remain in cancer treatment.