This essay critically reflects on the key approaches and professional capabilities in mental health assessment, emphasizing holistic wellness. It demonstrates an understanding of clinical formulation and holistic assessment, underpinned by critical thinking. The assessment covers psychological, physical, intellectual, and spiritual aspects, including physical examinations, psychological tests, and evaluations of social and cultural influences. The nursing psychiatric evaluation involves assessing the patient, identifying problems, diagnosing, setting outcomes, and formulating a care plan. Key components of a thorough assessment include biopsychosocial history, psychiatric history, substance use, medical history, family history, developmental history, social history, occupational and educational history, cultural history, and spiritual assessment, all aimed at providing patient-centered care and effective treatment.