This report provides a strategic analysis of AstraZeneca, focusing on its business strategies over the past five years, particularly in the context of the COVID-19 pandemic. It examines AstraZeneca's position within the pharmaceutical sector, analyzing its resources and capabilities using the VRIO framework to assess its competitive advantage. The report explores the company's implementation of cost leadership, differentiation, and focus strategies. Furthermore, it evaluates AstraZeneca's approach to environmental sustainability and offers recommendations for future strategic directions. Key findings highlight the importance of adapting to market changes and leveraging strategic frameworks for sustained success. The report analyzes the challenges and opportunities presented by the current business environment, emphasizing the need for strategic alignment and innovation.