This biostatistics assignment solution presents a detailed analysis of various statistical concepts using R. The solution addresses several questions, including calculating confidence intervals for mean grip strength and interpreting the results. It covers hypothesis testing using both parametric and non-parametric methods, such as Welch's t-test and Wilcoxon signed-rank test, comparing grip strength between genders and assessing the significance of location shifts. The assignment also includes a 1-sample proportions test to evaluate hypertension rates and calculates confidence intervals for the difference in proportions. Furthermore, it demonstrates the application of the Wilcoxon signed-rank test for paired data and explores sample size calculations for different scenarios, including determining the minimum sample size required for testing clinically significant differences in hypertension rates and generating confidence intervals. The solution also discusses the disadvantages of lower confidence levels. References and bibliography are provided for additional context.