Johns Hopkins Bipolar Disorder Treatment Quality Improvement Project

This report details a quality improvement project aimed at evaluating the effectiveness of monthly anti-psychotic injectable medication in treating adult patients diagnosed with Bipolar Disorder Type 1. The project, designed with a pretest and posttest survey intervention, seeks to improve symptom management and enhance the quality of life for patients aged 18-65. The study explores the use of anti-psychotic medication as a short-term treatment, considering factors such as patient health conditions and allergies. The report outlines the study's aim, hypothesis, target group, evidence, calculations, variables, and sample size, referencing key studies and providing estimates of effect size. The project's ultimate goal is to assess the impact of this medication on maintaining a stable mood and improving overall patient outcomes within a healthcare setting.

Running Head: BIPOLAR DISORDER TREATMENT
1
BIPOLAR DISORDER TREATMENT
Name of Student:
Name of Institution:
Date:

BIPOLAR DISORDER TREATMENT
2
Aim 1
1. (a) Measure
The amount of anti-psychotic medication administered to each student is dependent on
the decision made by the health practitioner involved. Some of the main areas considered by
these practitioners include whether the patients have other physical conditions, any allergies
or if the patient is on other conditions.
(b) Hypothesis
Null hypothesis: Administration of antipsychotic medication to patients living with Bipolar
Disorder helps to improve the quality of their lives.
Alternative hypothesis: Administration of anti-psychotic medication do not improve the
quality of life for people suffering from Bipolar Disorder.
© Target group
The main target group for these exercises the people living Bipolar Disorder within the
last six months from the time of the study.
(d) Evidence
Anti-psychotic medication is a short-term mode of treatment for people suffering from
this condition (Goldberg, 2017). It relieves the patients of the condition for a partial period of
time. Over that period, the patient feels more emotionally stable and free from the stress that
might hinder their plans.
(e) Calculations

BIPOLAR DISORDER TREATMENT
3
The main statics used when calculating for t-test would include the standard deviation for
group, mean difference between groups and the number of data values available.
(f) Variables used to measure
Variabl
e
Brief
Descriptio
n
Data
Source
Range of
Plausible
Values
Level of
Measuremen
t
Timefram
e for
Collection
Statistical
Test
Stress
levels
The extent
to which
the patient
is exposed
to stress
determines
how fast
he or she
heals
Observatio
n
Observatio
n
 Very
stress
ed
 Fairy
stress
ed
 Not
stress
ed
12 weeks Spearman
correlatio
ns
Mood
swing
The
patient has
varying
moods
from time
to time.
The
Observatio
n
Observatio
n
 Very
mood
y
 Mood
y
 Happ
12 weeks Spearman
correlatio
n

BIPOLAR DISORDER TREATMENT
4
objective
is to try
and
maintain a
steady
mood
y
Heartbe
at
(g) Sample size population
The sample size should be representative of the total population. This way, the
probability of having a biased outcome would be eliminated. A representative sample gives
an accurate estimate of the actual state of the population.
2. Best Estimates from previous studies

BIPOLAR DISORDER TREATMENT
5
Option 1
Values obtained from the
treated group
Values obtained from
comparison group or pre-
treated
Mark the term that best
describes how the effect
size value was obtained:
Estimates for the treatment
group (2-group comparison)
□ Estimates for post-treatment
(pre-post)
Estimates for control group
(2-group study)
□ Estimates for pre-treatment
(pre-post)
Identify the parameter
measured:
Mean (sd)
Proportion
□ Other, describe:
____________
Mean (sd)
Proportion
□ Other, describe:
____________
What is the value of the
effect size estimate?
The effect size is significant There is a significant effect on
the effect size
Provide citation or other
justification for these
estimates
(Geddes & Miklowitz, 2013)
(b) The slightest effects would be noted and used to measure the impact of the meditation on
the patient.
 




BIPOLAR DISORDER TREATMENT
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References
Geddes, J., & Miklowitz. (2013). Treatment of bipolar disorder. The lancet. The lancet, 381, 1672-1682.
Goldberg, J. (2017, September 20). Retrieved from WebMD: https://www.webmd.com/bipolar-
disorder/guide/antipsychotic-medication