This report presents a comprehensive nursing health assessment of the African-American population in the US, focusing on their vulnerability to cardiovascular disease (CVD). The assessment examines the key elements at community, group, and individual levels, including establishing assessment teams, engaging community members, defining the scope, conducting assessments, prioritizing health issues, and developing action plans. The report highlights the process for completing a comprehensive health assessment, detailing the use of the PACT model for individual assessments, encompassing physical health, substance use, psychiatric history, social development, activities of daily living, education/employment, and family relationships. Findings from secondary data analysis (literature review) and primary data (surveys) reveal that African-Americans face a significantly higher risk of CVD, linked to genetic, social, and environmental factors. The report concludes with recommendations for interventions at a large scale, emphasizing health awareness, evidence-based approaches, and the use of logic models to guide outcome-based strategies, along with the need for government support to ensure long-term impact. An appendix includes the survey questionnaire used to collect primary data.