Cardiovascular Disease: Genetic, Environmental, and Homeostasis

This essay delves into the multifaceted nature of cardiovascular disease, emphasizing the significant role of genetics alongside environmental factors. It highlights the importance of understanding the molecular basis of diseases like ischemic heart disease and hypertension, and the application of genetic approaches to inherited disorders. The essay underscores the crucial role of homeostasis and the function of proteins and enzymes encoded by genes. It explains how failures in homeostasis, whether at the genetic or environmental level, can lead to coronary heart disease. Furthermore, it discusses the concept of coronary heart disease as a multifactorial condition influenced by both genetic and environmental factors, and the need for polygenic strategies to determine genetic risk factors. The analysis also touches upon the impact of environmental factors, such as smoking, on disease risk, and concludes by reinforcing the view of cardiovascular disease as a complex interplay of genetic and environmental elements.

Running head: CARDIOVASCULAR DISEASE
Cardiovascular Disease
Name of the Student
Name of the University
Author note

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CARDIOVASCULAR DISEASE
The International experts have reported that the role of the genetics plays a major
importance in the cardiovascular diseases. The molecular basis of the ischemic heart diseases,
hypertension and thrombosis, the mapping of the genetic approaches to the inherited form of the
disorders are also to be noted (Estruch et al., 2013). The biological forms of the targeted agents
are also of utmost importance for the hypertension and the failure of the heart.
The health is maintained through the process of the integration of the numerous form of the
complex form of the homeostatic process of physiology to operate at a tissue, organ and the
cellular level. These forms of processes depends heavily upon the production of the operation of
the appropriate and the correct amount of the functional form of proteins and the enzymes that
are being encoded by the genes (Zordoky, Robertson & Dyck, 2015). The diseases such as the
coronary heart diseases generally results from the failure of the adequate form of the homeostasis
within the physiological form of the system.
This may also occur due to the failure in the genetic levels, for instance, the transmission
of the genes or due to the exposure to the basic environment or even due to the imbalances that
may occur between the two aspects. It is rare that the coronary heart diseases results from the
single form of mutation in the process of single mutation in the single form of the major
homeostatic gene those includes the regulation of the lipoprotein form of synthesis (Matsuda &
Shimomura, 2014). Moreover, it has been observed that the Coronary heart diseases have a very
modest form of input from the minor form of mutations in various discrete genes for modulating
the risk factors.

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These act a key for controlling the expression of the other form of genes or the effect of
the structures for the functioning of the transcribed form of the proteins. These functional forms
of the genes account of polymorphism accounts for much of the diversity in the system in the
system of the homeostasis. In this form of absence all the humans tends to respond in an identical
manner for the challenges in the environment challenges and the risk for developing the diseases
that would be directly proportional to the various stimulus of the environment. For instance, the
individuals who are been exposed to smoking of cigarettes are categorized into the profile of the
identical form of the risk factors that will be needed for the development of the coronary heart
diseases, while the other individuals will do not be considered (Matsuda & Shimomura, 2014).
Therefore, the well accepted form of view for that of the coronary heart disease is a multifactor
disease and that have both genetic and the environmental factors that are been contributing to it.
Any singular form of the mutation in a single gene will play a key factor for determining
the risk factors for the early form of the Coronary heart diseases. For determining the genetic
form of the risk factors for the profile of the subject, there should be the implementation of the
polygenic form of strategies (Roohbakhsh et al., 2015). Therefore, only with the process of
simultaneous form of analysis of the genes polymorphism at various loci that are functional or by
satisfying the presence of the factors in the environment such sort of understanding can be
obtained.

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References
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