This case report presents a detailed analysis of Mr. Hank Jackson, a 64-year-old retired truck driver with a diagnosis of diabetic retinopathy and hypertension. The report begins with an introduction to Mr. Jackson's medical history, including his type 2 diabetes diagnosis and current medication regimen. The primary medical diagnosis of diabetic retinopathy is explored, detailing its causes, stages, and potential complications. The report then delves into medication management, outlining various treatment options such as photocoagulation, vitrectomy, and the use of vascular endothelial growth factor inhibitors. A nursing diagnosis is provided, highlighting the risk of unstable blood sugars, imbalanced nutrition, and imbalanced blood volumes, with a focus on the challenges posed by Mr. Jackson's lifestyle. The nursing role and inter-professional plan of care are then discussed, emphasizing the importance of a collaborative approach involving the patient, family (if applicable), and healthcare professionals. The care plan includes assessments for hyperglycaemia, retinopathy progression, and patient education. The report draws upon relevant academic literature to support an evidence-based plan of care and provides insights into the nursing interventions and strategies needed to effectively manage Mr. Jackson's condition and improve his health outcomes.