This case study examines the case of George, a 51-year-old Aboriginal and Torres Strait Islander male with CKD and hypertension, applying the clinical reasoning cycle to his care. The assignment details the steps involved, including considering the patient's background, collecting cues and information (vital signs, medical history, medications), processing the information (interpretation, discrimination, relation, inference, matching situations, and predicting outcomes), taking action (recommending ACE inhibitors and ARBs), and reflecting on the process. George's history includes a stroke, diabetes, and smoking, which contributed to his worsening health, including increased weight, elevated blood pressure, and reduced kidney function. The study emphasizes the importance of understanding the medications prescribed (perindopril, furosemide, atorvastatin, metformin, sodium bicarbonate, and vitamin D), and the need for patient education and support. The clinical reasoning cycle is used to analyze George's condition, propose interventions, and highlight the importance of monitoring his progress and encouraging lifestyle changes to manage his hypertension and CKD effectively. The study aims to improve clinical reasoning skills for nursing students, enabling them to provide effective patient care and management.