This case study analyzes the post-operative complications of Mrs. Gina Bacci, a 49-year-old Italian woman with diabetes who underwent a forefoot amputation. The analysis focuses on the underlying pathophysiology of her wound infection, including broken sutures, serous exudates, and the impact of her diabetes and obesity. Two primary nursing priorities are identified: managing her wound infection through aseptic techniques and patient education, and controlling her elevated blood sugar levels through dietary modifications and insulin administration. The study details appropriate and safe nursing care management, including wound care, medication adherence, and patient education to mitigate the risk of infection and improve her overall health. The assignment emphasizes the importance of a multidisciplinary approach to address Mrs. Bacci's complex needs, with a focus on patient education to ensure the patient's compliance with the interventions and improve her health outcomes. The case study concludes by highlighting the nursing interventions to control diabetes, wound healing and prevent further complications.