This report presents a comprehensive analysis of a clinical scenario involving a 7-year-old Syrian boy, Karam, hospitalized with appendicitis. It focuses on providing evidence-based nursing care, emphasizing the child's developmental stage and incorporating child-centered care principles to address post-operative pain and emotional needs. The report highlights the importance of effective communication, particularly the need for clear discharge instructions and pain management strategies for the family. It identifies communication gaps and proposes solutions, including providing comprehensive information and involving the family in decision-making, aligning with family-centered care principles. The conclusion stresses the significance of holistic, collaborative approaches to enhance patient outcomes and family involvement, including a complete sharing of information, to ensure the child's well-being and recovery.