This nursing assignment analyzes the clinical reasoning process in the care of a 79-year-old patient, Mrs. Kate Ham, who underwent a right total knee arthroplasty (RTKA). The assignment focuses on the application of the DETECT framework (Detect, Evaluate, Treatment, Escalate, Communicate, Teams) to assess the patient's condition, identify potential complications such as pain, neurovascular issues, and hypoglycemia, and implement appropriate nursing interventions. The report details the nursing assessment, including monitoring pain levels, neurovascular status, and blood glucose. It explains the rationale behind clinical decisions, such as managing post-operative pain, preventing neurovascular damage, and addressing tachycardia. The assignment emphasizes the importance of communication within the healthcare team, using the ISBAR tool for clear and concise handover information. The analysis highlights the critical role of clinical reasoning and evaluation of patient outcomes in providing safe and high-quality care, particularly for patients with co-morbidities like asthma and NIDDM. The assignment also explores the importance of early recognition of complications, such as venous thromboembolism, and the necessity for timely escalation of concerns to the surgical team. The report concludes by emphasizing the need for regular patient assessment and the application of nursing knowledge in making the best decisions for the patient's well-being.