This report delves into the concepts of telemedicine and clinical decision support systems (CDSS) within the healthcare landscape. It begins by defining telemedicine, differentiating between real-time and prerecorded approaches, and highlighting the advantages of prerecorded telemedicine, also known as store-and-forward or asynchronous telemedicine, for healthcare providers and patients. The report then transitions to CDSS, explaining its function in aiding healthcare professionals in making decisions and enhancing patient care interactions. It explores various types of CDSS, including computerized physician order entry and alert fatigue technology, emphasizing their role in improving patient safety and adherence to medical guidelines. The report references several studies to support the information provided and concludes by underscoring the importance of these technologies in modern healthcare.