This essay investigates the effectiveness of colorectal cancer screening in detecting and treating colon cancer in women aged 55 to 65. It begins with an introduction and background on colorectal cancer, highlighting its significance and risk factors. The methodology section details the use of the PICO framework and a literature review strategy, including keyword searches and Boolean operators, to gather relevant articles. The essay critically appraises three selected articles, examining their aims, methodologies, strengths, and limitations. The critical appraisal focuses on the validity, usefulness, and clinical applicability of the research papers. Finally, the essay discusses the overall findings, provides recommendations, and concludes with a summary of the key points. The essay also addresses ethical considerations such as informed consent and data confidentiality.