This report provides a comprehensive comparison of the roles of Nurse Practitioners (NPs) and Clinical Nurse Specialists (CNSs) in the Canadian healthcare system, focusing on the Saskatchewan Nursing Advanced Practice (SNAP) Model. The analysis covers five key domains: direct comprehensive care, evidence-informed practice, educative practice, support systems, and professional leadership. The report highlights the differences in autonomy, responsibilities, and environments in which NPs and CNSs operate, including their involvement in diagnosis, treatment, education, and research. It examines how CNSs contribute to clinical guidelines and research, while NPs focus on direct patient care and health promotion. The report also addresses their contributions to support systems, educative practices, evidence-based practice, and professional leadership within the Canadian healthcare context. The report underscores the significance of these distinctions for aspiring advanced practice nurses and the overall improvement of healthcare delivery.