This report examines Coronary Artery Disease (CAD), a major chronic condition contributing to the global burden of disease. It begins with an introduction to CAD and its impact on the circulatory system, followed by an analysis of statistics and data related to prevalence and mortality rates worldwide, with a focus on the United States, the UK, and Australia. The report then explores the public health significance of CAD, detailing its impact on individuals, families, and communities, as well as its financial implications. Various risk factors such as age, gender, ethnicity, family history, smoking, and abnormal cholesterol levels are discussed. The determinants including behavioral, psychological, socioeconomic, and environmental factors are also analyzed. The report then introduces and critically reviews the Chronic Care Model (CCM) as a framework for the prevention and management of CAD, examining its key components: community resources and policies, healthcare organization, self-management support, delivery system design, decision support, and clinical information systems. The report concludes by summarizing the key findings and implications of the analysis.