This report provides a comprehensive analysis of corporate social responsibility (CSR) and sustainability issues within the context of multinational manufacturing companies. It explores the multifaceted dimensions of CSR, including social, economic, and environmental perspectives. The report delves into specific challenges such as sustainable supply chains, business ethics, employee satisfaction, environmental protection, and the circular economy. It examines the integration of sustainability practices, the impact of globalization, and the importance of balancing environmental concerns with economic goals. The report further discusses the environmental, social, and economic sustainability issues faced by multinational manufacturing organizations, encompassing pollution, waste disposal, consumer demands, labor practices, and the effects of economic factors such as inflation, interest rates, and unemployment. The analysis highlights the critical need for ethical business practices, environmental responsibility, and social awareness in the manufacturing sector, emphasizing the importance of long-term sustainability and responsible corporate behavior.