This report delves into the implementation of Computerized Physician Order Entry (CPOE) at University Health Care System, exploring methods for evaluating its effectiveness and return on investment (ROI). It examines various strategies, including manual-CPOE integration, training and education, and electronic delivery, to assess the system's impact on patient safety, efficiency, and quality of care. The report addresses the board's request for ROI, arguing its reasonableness while acknowledging the challenges in immediate financial returns. The author proposes a plan for assessing CPOE value, involving continuous monitoring, IT and consumer input, and the establishment of baseline data like patient and prescription records to ensure error-free operation and guarantee patient safety. The analysis emphasizes the importance of a continuous monitoring system and the involvement of various stakeholders, including IT personnel, clinicians, and psychologists, to analyze the system's performance and identify areas for improvement. The conclusion highlights the potential for healthcare systems to enhance patient care through the implementation of CPOE systems, alongside EMR systems, ensuring safety and efficiency in prescription and patient records.