Critical Analysis of Research Paper: Dual Antiplatelet Therapy Review

This report presents a critical analysis of a research paper focused on Dual Antiplatelet Therapy (DAPT) before coronary artery bypass grafting. The analysis employs the Critical Appraisal Skills Program (CASP) tool to evaluate the paper's strengths and weaknesses, methodology, and appropriateness of methods. The report examines the systematic review process, including the use of databases like Medline, Embase, and Scopus, and the application of meta-analysis. The assessment includes a detailed review of the checklist used in CASP, the handling of data duplication, and the overall quality of the research. The report also discusses the research methodology, differentiating between primary and secondary research methods, and the importance of these methods in the context of the research question. The conclusion summarizes the findings regarding the effectiveness of DAPT and its implications for patient outcomes, such as mortality rates and renal failure, highlighting the importance of systematic reviews and meta-analyses in healthcare research.

Critical Analysis of
Research Paper

Table of Contents
INTRODUCTION...........................................................................................................................3
MAIN BODY...................................................................................................................................3
Analyse and critically Review using the appropriate Critical Appraisals Skills Program
(CASP) tool............................................................................................................................3
Argue and Justify whether the methodology and methods are appropriate to address the
research problem....................................................................................................................6
Discuss and justify the strengths and weaknesses using relevant supporting evidence.........8
CONCLUSION................................................................................................................................9
REFERENCES..............................................................................................................................10

INTRODUCTION
Research is the fundamental factor that revolves around developing systematic inquires and
collecting details, documenting information and proper identification and interpretation as well
in terms of reaching to the certain evident and conclusion. Along with this, research need
prominent skills in terms of ensuring suitable collection of reliable and enough data regarding the
prominent support of work which is being presented and also address suitable issues by which
research is being conducted (Kalaitzidis & Jewell, (2020)). The present report is based on
researching on the nursing field in which the prominent article is being reviewed for the “Dual
Antiplatelet Therapy before coronary artery bypass grafting- a prominent review and meta-
analysis”. This article tends to review things by effectively using Critical Appraisals skills
program (CASP). Moreover, the report is used by the researcher in terms of organising the
overall research and also depict the effective evidences by analysing the report appropriately.
Furthermore, it also describes the strengths and weaknesses of suitable methods by which the
whole research is developed and article is being presented.
MAIN BODY
Analyse and critically Review using the appropriate Critical Appraisals Skills Program (CASP)
tool
CASP tool is useful in evaluating the prominent strengths and weaknesses by considering
proper research process which should be performed effectively. It is useful in terms of
determining the overall research with the help of proper sources and according to the sources it
leads to make sure the effectiveness of opting natural resources. Furthermore, considering the
checklist which is being effectively researched is prepared and classified into several research as
it is based on qualitative. This tool is useful to make sure several presentation of research which
is being suitable and worthy for the findings (Squires & Dorsen, (2018)). CASP undertake
appraisals that tends to offer things and undertake prominent ways for effective dedications in
suitable studies which is being cohort in nature. Hence, the diagnostic studies tend to analyse the
suitable economic changes and some of the checklist is being discussed below in the grounds of
opted topic.
In regard of this, the suitable analysis of first checklist is analysed as the systematic review
which is prominently put emphasis on suitable questions by offering suitable solutions. Along

with this, the suitable report leads to analyse the critical identification over the dual anti-platelet
therapy before the artery bypass grafting. According to this topic, it suitably focuses on the
creating effective report and also relies on the effective questions which are concerned with
interventions. The prominent report tends to highlight several questions in an effective manner
which are effective in order to give prominent outcome from the whole assessment for the
upcoming references.
By considering the above identification of research topic, it is based on several loops that
are useful in terms of determining the exact information which is quite relevant and prominent
information with the development of project. After analysing several research paper, it is
effectively defined that there are various researchers who have their own ideas and viewpoint
regarding the specific things. Furthermore, at the time of developing suitable report, it leads to
effectively define things with proper research and relevance also required in terms of making
effective evidence (Martínez‐Rodríguez & Olivé‐Ferrer, (2020)). Along with this, the particular
topic leads to provide clear understanding of subject matter which is reliable for the development
of report. In present times, effective analysis is based on the particular vision for developing and
gathering data as it is important for effective report writing. The report also state regarding
prominent studies as it is based on the suitable essay that is being developed on an assay and it is
also termed as DAPT assay with Aspirin and clopidogrel before CABG take entry. It depicts the
need regarding the perfect development of meta-analysis selection of keyword with proper
references as it is required in terms of showing evidence which is based on data forming and
offer article which is being related with journals. In regard of this, journals are effectively being
gathered by Medline, Embase and Scopus as data is provided in appendix for the systematic
report and by this when an individual try to search from above journal it would be easy for them
to get result by just keyword such as Medline.
Along with this, the another checklist is useful in terms of covering suitable data which is
appropriate in nature in regard of the report. Along with this, the report is based on prominent
topics like coronary artery bypass, aspirin and clopidogrel, acute coronary syndrome, anti-
platelet therapy and so on. Hence, the report tends to cover the suitable data from bibliographic
unit and it is useful in terms of checking the accuracy of report when the research is being
prepared (Fain, (2020)). In regard of this, meta-analysis is the effective approach which is being
categorised into three parts, like systematic searches over the electronic database as it is required

by searching through google that offer suitable approaches over their webpage for the further
study and effective screening which is being used in terms of bibliography. Moreover, when
things are passing by another checklist and then it will measure in regard of qualitative factor.
Furthermore, the detailed analysis of overall study is done which is being reviewed with the help
of quality report. Moreover, by presently reviewing the detailed statement are being collected
from the EndNote software that is initiated as effectively eliminating artificial Xerox
investigation details and data in order to improve the quality of research. In the CASP tool
suitable measurement is effective in terms of knowing several factors which are useful in terms
of gaining better decision and review quality.
Moreover, undertaking the new checklist leads to effectively identify the suitable result in
terms of reviewing and also being combined or not. In regard of this, it tends to depict the proper
knowing and reviewing of suitable aspects. It is effective examined that no duplication of study
is based on the research as it is not allowed in sort of situation. Moreover, it is also being assured
by EndNote software which is rapidly used. Furthermore, the prominent research does not
undertake duplicate records considering the detailed analysis as these are useful in terms of
screening the overall studies (Jefferies & Glew, (2018)). In regard of this, the review is being
organised that consider 4 random trails that relies on clinic and 6 to 7 retrospective cohort studies
are followed. Furthermore, in terms of enhancing the overall quality of report, it depicts the
essential factor that drive through actual and real studies which undertake around 8029 patients
in total number.
Besides from this, the qualitative measure is effectively depending on the suitable
objective which is drawn at the end of review. According to the discussed report, depict
regarding the results that DAPT with aspirin and clopidogrel that is offered before CABG before
knowing the patience with ACS that lead towards the renal failure as there are several cardiac
events that include hypertension and so on which are concerned with the enhancement of rates of
mortality and also summarise it with DAPT which is always connected. Hence, the result is
being offered in precise manner after the proper screening of report that undertake 41 articles for
the suitable collection of data which is from the 15 studies that undertake meta-analysis. Along
with this, the another checklist tends to use defined things undertaking the several aims that are
effectively applied over the local population or not. Moreover, it is said that the checklist is
beneficial in report in terms of taking real facts and factors which undertake suitable population

and various investigator that effectively conducted and also need enhancement by considering
several techniques in CASP tools that are helpful to enhance the research quality.
According to this, there are several number of checklist which is being discussed in order
to make proper execution in an effective manner that leads to create suitable benefits by enhance
the research origin and eliminate problems that occur in research. Along with this, it is being
summarised that the topic is based on suitable reviewing and identification in an effective
manner which is being organised through real methods and its instances are concerned with
effective population and proper research is being organised (Chang, Lai & Hwang, (2018)).
Away with this, the report tends to analyse and create suitable outcome which is essential in
terms of acknowledging and considering the fact in an impactful manner. In regard of this, it also
tends to highlight outcomes undertaking the mortality rates, CVA, MI and other diseases like
renal failure, re-exploration and many more. According to this, at the time of conducting
research it need to consider meta-analysis which is useful in terms of deriving from the presented
meta-analysis as it has higher cost instead of harming as this approach is useful in modern times.
Along with this, it leads to review and also useful in order to analyse things by individuals that
tends to deal with various medical issues because of inadequate quality of healthy and
unnecessary identification which is the waste of time. According to the recent meta-analysis that
tends to offer prominent justification in regard of medication by their overall systematic review
and meta-analysis.
Argue and Justify whether the methodology and methods are appropriate to address the research
problem
Research methodology depict as the suitable process which is helpful in terms of analysing
the overall process that tends to select and identify things regarding the overall project. It leads to
permit things for the effectiveness about the overall research process by offering proper
knowledge with detailed identification of the subject matter (Medvedyuk, Ali & Raphael,
(2018)). Furthermore, it tends to provide answer regarding the suitable questions as proper
sources of data is being collected and identified. Hence, it effectively undertakes two types of
market research which are:
Primary research: It depict as the direct interaction among several organisations and
potential customers by which they used to extract demand and suitable value of company and its
concerning products and services within various market area. This kind of market research is

organised from making effective identification that leads to offer prominent information as it is
based on the prominent research which is discussed as underneath:
 Interviews: It depict face to face interview among two or more people and it is also
considered as the time taken approach undertaking the need of investment in terms of
collecting individuals and having proper survey which depends on the suitable interview
(Banks, Lombard & Mitlin, (2020)). It undertakes the prominent source of economic that
leads to analyse overall condition by improving overall productivity and profitability of
an organisation. It effectively represents the wastage of resources which is being
neglected by having effective use of survey in order to eliminate wastage.
 Survey: In present time, survey is done through online method as it leads to generate by
suitable links which through browsing and playing online videos. It leads to cover
suitable dimensions in order to know the value of product as it is consumed by customers
within the market area.
 Questionnaire: It is applied over the set of questions which is helpful in terms of
dedicating towards the suitable products and services as it is delivered to their customers.
According to the following report, it is identified that the author undertakes several steps
that are concerned with suitable research tools and useful in order to extract data from the
general and local people. Furthermore, the report quality is being imported by the EndNote
software as it is being reviewed by the duplication of data that is being extracted in this report.
Secondary research: It depict the research which is useful in terms of extracting data in
terms of conducting overall study. It undertakes the inclusion of research and reports which is
being effectively performed by several organisations, agencies and government as it is linked
with the specific sector (Cushion, (2018)). Furthermore, small businesses with limited budget of
capital tends to opt this type of research as it is affordable tool and also commonly used in the
effective coordination for the frequent decision in various operations in the sector.
Away with this, the given meta-analysis tends to effectively collaborate with effective
approaches with several authors in both primary and secondary type of research that effectively
extract information and data which is being discussed in article like newspaper, magazine and so
on. Hence, the author leads to use various research strategies in terms of managing suitable
sources effectively undertaking the objective of research (Waite & Nardi, (2019)). Here, data is
effectively measured and extracted from the official site of NIH and the research is helpful in

terms of understanding the suitable concept of cross sectional studies. Hence, this quality of
research is useful in order to develop suitable paper with no duplication and research quality.
Discuss and justify the strengths and weaknesses using relevant supporting evidence
Meta-analysis leads to use both types of research methodology that is useful in describing
the strengths and weaknesses which is discussed as below:
For Primary research:
Strengths Weaknesses
 In terms of primary research, author
tends to effectively use meta-analysis in
an effective manner that leads to
establish direct terms with several
people by offering them suitable source
of information (Peters, (2018)).
 Here, the strength of author is linked
with it proper tools and technologies
regarding the extraction of information
which is quite relevant and trustworthy.
 The weakness is being analysed
according to the primary research as it
is time consuming and not for the small
scale companies for their research.
 The another weakness is linked with the
suitable type of research that undertake
high cost in development of report and
its data is quite flexible in nature
(McAndrew, Leske & Schroeter,
(2018)).
For secondary research:
Strengths Weaknesses
 This technique is helpful in terms of
saving cost and time as it tends to
neglect the interaction with several
individuals and eliminate issues of
meeting things with productive people
(Roy, (2018)).
 It saves time with the help of valuable
resources at the time of conducting
systematic reviews or meta-analysis.
 The research offers information
regarding the suitable resources that
 Here, data is extracted on the ground of
early experience in which researcher
tends to collect data and information
which has no existence.
 It depicts the error because of the
duplication of information that occur
and leads to decrease the overall quality
of report and research (Zhang & Wang,
(2018)).
 The research is being organised in an
effective manner by including both

offer better experience to viewer. primary and secondary research.
According to this, it is useful for the
extraction of data that occur high cost.
CONCLUSION
According to the above discussion, it is being analysed that the analysis of meta-analysis is
being offered on the grounds of pointing by various check-point which is discussed in above
part. The report is passed by performing various checklist and also undertake suitable strengths
and weaknesses which are being analysed with suitable sources. Hence, it is being concluded by
the suitable information and resources which is organised at the time of ethical research.

REFERENCES
Books and Journals
Banks, N., Lombard, M., & Mitlin, D. (2020). Urban informality as a site of critical
analysis. The Journal of Development Studies, 56(2), 223-238.
Chang, C. Y., Lai, C. L., & Hwang, G. J. (2018). Trends and research issues of mobile learning
studies in nursing education: A review of academic publications from 1971 to
2016. Computers & Education, 116, 28-48.
Cushion, C. J. (2018). Reflection and reflective practice discourses in coaching: A critical
analysis. Sport, education and society, 23(1), 82-94.
Fain, J. A. (2020). Reading, understanding, and applying nursing research. FA Davis.
Jefferies, D., & Glew, P. (2018). The importance of academic literacy for undergraduate nursing
students and its relationship to future professional clinical practice: A systematic
review. Nurse Education Today, 60, 84-91.
Kalaitzidis, E., & Jewell, P. (2020). The concept of advocacy in nursing: a critical analysis. The
health care manager, 39(2), 77-84.
Martínez‐Rodríguez, A., & Olivé‐Ferrer, M. C. (2020). Construction of nursing knowledge in
commodified contexts: A discussion paper. Nursing inquiry, 27(2), e12336.
McAndrew, N. S., Leske, J., & Schroeter, K. (2018). Moral distress in critical care nursing: the
state of the science. Nursing Ethics, 25(5), 552-570.
Medvedyuk, S., Ali, A., & Raphael, D. (2018). Ideology, obesity and the social determinants of
health: a critical analysis of the obesity and health relationship. Critical Public
Health, 28(5), 573-585.
Peters, E. (2018, October). Compassion fatigue in nursing: A concept analysis. In Nursing
forum (Vol. 53, No. 4, pp. 466-480).
Roy, C. (2018). Key issues in nursing theory: Developments, challenges, and future
directions. Nursing Research, 67(2), 81-92.
Squires, A., & Dorsen, C. (2018). Qualitative research in nursing and health professions
regulation. Journal of Nursing Regulation, 9(3), 15-26.
Waite, R., & Nardi, D. (2019). Nursing colonialism in America: Implications for nursing
leadership. Journal of Professional Nursing, 35(1), 18-25.
Zhang, Y. Y., & Wang, Y. L. (2018). Extent of compassion satisfaction, compassion fatigue and
burnout in nursing: A meta‐analysis. Journal of nursing management, 26(7), 810-819.