Active Learning Template Assignment: Crohn's Disease Analysis, Nursing

This assignment delves into Crohn's disease, an inflammatory bowel disease (IBD) characterized by inflammation of the gastrointestinal tract, leading to symptoms like abdominal pain, diarrhea, fatigue, and weight loss. The analysis encompasses the disease's pathophysiology, including the inflammation process that can affect various parts of the digestive system, starting from the mucosa and potentially damaging the intestinal lining, hindering nutrient absorption. The assignment also provides an overview of the available treatments, which include medications to alleviate symptoms, bowel rest to give the digestive system a break, and surgical interventions to address complications such as fistulas or obstructions. The document also includes references to relevant research papers and studies.

Running head: CROHN’S DISEASE
Crohn’s Disease
Name of the student
Name of the university
Author’s name

1CROHN’S DISEASE
Crohn's disease falls under IBD (Halfvarson et al., 2017). It leads to inflammation in the
gastrointestinal tract that causes abdominal pain, diarrhea, fatigue, weight loss and
malnourishment. Inflammation due to the Crohn's disease can spread to various portions of the
gastrointestinal tract among different people (Torres, Mehandru, Colombel & Peyrin-Biroulet,
2017).
The inflammation starts in the region of mucosa which covers the interior layer of the intestine.
Later the disease occupies the interior tissues of the intestinal inner surface. The inflammation
harms the interior layer of the intestine which restricts the absorption of nutrients, water, and fats
during the ingestion of food (Boyapati, Satsangi & Ho, 2015). If the inflammation turns chronic
then it can cause ulcers anywhere in the digestive tract, including the mouth and anus (Torres,
Mehandru, Colombel & Peyrin-Biroulet, 2017).
Crohn's disease can be treated with the help of medicines, bowel rest and surgery (Cruz et al.,
2015).
1. Medicines (help in reducing symptoms) (Cheifetz, Gianotti, Luber & Gibson, 2017) (Onidi et
al., 2018)
2. Bowel rest (if symptoms are severe, then the bowel is given rest by drinking only certain
liquids comprising nutrients and not eating anything)
3. Surgery (to treat fistulas, bleeding, intestinal obstructions) (Onidi et al., 2018)

2CROHN’S DISEASE
REFERENCES
Boyapati, R., Satsangi, J., & Ho, G. T. (2015). Pathogenesis of Crohn's disease. F1000prime
reports, 7.
Cheifetz, A. S., Gianotti, R., Luber, R., & Gibson, P. R. (2017). Complementary and alternative
medicines used by patients with inflammatory bowel diseases. Gastroenterology, 152(2),
415-429.
De Cruz, P., Kamm, M. A., Hamilton, A. L., Ritchie, K. J., Krejany, E. O., Gorelik, A., ... &
Bampton, P. A. (2015). Crohn's disease management after intestinal resection: a
randomised trial. The Lancet, 385(9976), 1406-1417.
Halfvarson, J., Brislawn, C. J., Lamendella, R., Vázquez-Baeza, Y., Walters, W. A., Bramer, L.
M., ... & McClure, E. E. (2017). Dynamics of the human gut microbiome in
inflammatory bowel disease. Nature microbiology, 2(5), 17004.
Onidi, F. M., Simbula, S., Vacca, V., Binaghi, L., Pellecchia, M., Cabras, F., ... & Mocci, G.
(2018). N036 The advanced nursing care in IBD: Study on biosimilar drugs. Journal of
Crohn's and Colitis, 12(supplement_1), S584-S585.
Torres, J., Mehandru, S., Colombel, J. F., & Peyrin-Biroulet, L. (2017). Crohn's disease. The
Lancet, 389(10080), 1741-1755.