This essay examines the concept of cross-cultural competence and the barriers to effective cross-cultural interactions within the context of Singaporean society. It begins by defining cross-cultural competence, drawing upon the work of Johnson, Lenartowicz, and Apud, who emphasize the importance of knowledge, skill, and attitude. The essay then delves into the factors influencing intercultural communication and the role of personal identity and cultural awareness. It also discusses the concept of cross-cultural training and the dimensions of cultural knowledge, including culture-general and culture-specific knowledge, and the acquisition of knowledge. The essay further explores the skill dimension of cross-cultural competency. The second part of the essay focuses on the barriers to cross-cultural interactions, as defined by Rozkwitalska, including cultural contingencies, national culture-related factors, organizational factors, and individual factors such as perception barriers and ethnocentrism. The essay then presents two case studies: one illustrating cultural competence in social work practice and the other highlighting cross-cultural communication barriers in the workplace. These case studies demonstrate the practical implications of the concepts discussed, emphasizing the importance of cultural sensitivity and the challenges of navigating cultural differences in a multicultural environment. The essay concludes by underscoring the relevance of these case studies in understanding both the achievements of and obstacles to successful cross-cultural interactions.