This report provides an analytical study on the cultural safety of patients within healthcare settings, focusing on the importance of patient safety and the factors affecting it. The report examines the role of nurses as leaders in maintaining a safe and healthy environment, using a case study of Mrs. Jackson to illustrate the impact of unhealthy conditions and poor leadership. It also highlights the measures taken by Hospital Hope to improve its healthcare facility through the IHI program, emphasizing the implementation of evidence-based practices, teamwork, and communication. The report concludes by stressing the significance of cultural safety in building patient relationships and the critical role of unit-level nurses in ensuring patient safety and care. The study draws on a range of sources to support its findings and recommendations for improving patient outcomes.