This report examines the critical issue of death during dialysis, focusing on the causes, ethical considerations, and management strategies associated with mortality in dialysis patients. It highlights that deaths due to dialysis are a significant global concern, ranking as the second leading cause of death worldwide. The report explores the ethical dilemmas surrounding end-of-life care, particularly the challenges in balancing patient desires for continued dialysis with the potential for prolonged suffering, especially among older patients. It discusses various palliative care options, including hospice services and different levels of care provided by healthcare professionals. Management strategies to mitigate risks, such as increasing glomerular filtration rates and monitoring heart rate variability, are also addressed. The report further investigates the quality of death during dialysis, noting that it is often poor, particularly in older individuals, and emphasizes the need for effective palliative care. It touches upon the controversial topic of euthanasia in comparison to end-of-life procedures and underscores the importance of preventive measures, such as maintaining a healthy diet and controlling blood sugar levels, to improve patient outcomes during dialysis. The study concludes by emphasizing the need for improved end-of-life care and adherence to healthy practices to minimize deaths during dialysis.