Deep Learning in Bioinformatics: Applications and Techniques Used

This presentation provides an overview of how deep learning is applied in bioinformatics, with a specific focus on biomedical imaging. It discusses the use of deep neural networks and convolutional neural networks in analyzing biomedical images such as magnetic resonance images, radiographic images, and positron emission tomography scans. These techniques are used in anomaly classification, brain decoding, cancer screening, and detection of various conditions like sclerotic metastates and colonic polyps. The presentation references key works in the field, highlighting the increasing importance of deep learning in medical research and diagnostics.

DEEP LEARNING AND
BIOINFORMATICS
Presented by…

Example of bioinformatics
 Biomedical imaging
 Deep learning has been used in biomedical imaging (Panda,
M., 2012).
 There has been an actively researched domain in this aspect
since the deep learning has been used in image related tasks
 Most of the biomedical images are used by the doctors in the
hospitals use to treat patients in the real life
 Many hospitals use magnetic resonance image, radiographic
image, positron emission tomography (LeCun, Bengio and
Hinton, 2015).
 The doctors use this application to input data to the deep
learning algorithms.

Diagram example

Biomedical imaging in deep neutral network in bioinformatics
 Deep neutral network has been utilized by the doctors
and physicians in numerous research areas which
include the anomaly classification, brain decoding and
recognition (Min, Lee and Yoon, 2017).
 The doctors have used numerous image sources which
have been used to classify schizophrenia patients
through use of DBN on the brains MRIs (Panda, M.,
2012).
 They have also used them in the SAE in the cell
nuclei detection from the histopathology images.

Convolutional neural network in biomedical imaging in
bioinformatics
 numerous researches done by practising doctors or medical
research scientists on biomedical imaging since the issues are
similar form to the image related task (LeCun, Bengio and Hinton,
2015).
 Hospitals have utilized deep learning in bioinformatics via
application of the biomedical imaging in CNN to different CT
image datasets in order to classify sclerotic metastates, colonic
polyp and lymph node.
 Hospitals use CNN in mitosis detection among the breast cancer to
the histopathology images (Panda, M., 2012).
 This has been vital to the cancer screening as well as assessment.
 They have also been utilized PET images of the esophageal cancer.

References
Goodfellow, I., Bengio, Y., Courville, A. and Bengio, Y.,
2016. Deep learning (Vol. 1). Cambridge: MIT press.
LeCun, Y., Bengio, Y. and Hinton, G., 2015. Deep
learning.
nature, 521(7553), p.436.
Min, S., Lee, B. and Yoon, S., 2017. Deep learning in
bioinformatics. Briefings in bioinformatics, 18(5), pp.851-
869.
Panda, M., 2012. Deep Learning in Bioinformatics. CSI
Communications, 4.