Delmira: A Peptide-Based Approach to Overcoming Leptin Resistance
VerifiedAdded on 2023/03/31
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This report examines Delmira, a novel peptide designed to combat leptin resistance and facilitate weight loss. Delmira, derived from the Greek word for protector, aims to sensitize impaired leptin receptors, addressing a key issue in obesity. The peptide acts by restoring leptin receptor action through STAT3 phosphorylation, controlling leptin release, and mitigating ER stress-induced inflammation. By targeting the production of leptin in adipocytes and overcoming inhibitions faced by leptin receptors in obese individuals, Delmira aims to increase energy expenditure and reduce food intake. The report references studies on leptin's effects on immune cells and its role in reducing food intake and increasing energy expenditure. This student contributed assignment is available on Desklib, where you can find more solved assignments and past papers.
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