This report delves into the intricate relationship between diabetes and chronic kidney disease, providing a comparative analysis of blood sugar levels in both diabetic and non-diabetic individuals. It examines the effects of medications like Glucovance, including its components (glyburide and metformin), potential side effects, and contraindications. The report also explores the need for new medications to address the specific needs of diabetic patients with kidney disease, considering the importance of red blood cell production, vitamin D activation, and acid-base balance. Furthermore, it outlines the registered nurse standards for practice, emphasizing the nurse's role in developing and communicating treatment plans in partnership with the patient. The analysis references several research papers to support the findings.