This research statement presents a qualitative study focused on the impact of Dry Eye Disease (DED) and its screening techniques on the quality of life (QOL) of Australian patients. The study aims to explore whether DED affects the QOL and if screening methods influence it. The background highlights DED as a major ocular-surface disease affecting a significant portion of the global population, leading to visual disturbances and affecting various aspects of well-being. The literature review emphasizes the multi-factorial nature of DED, its impact on daily activities, and the challenges in diagnosis due to the lack of a gold standard. The study intends to provide insights for healthcare professionals, analyze effective screening techniques, and contribute to the development of a gold-standard policy to minimize patient discomfort and economic burden. The conclusion emphasizes the potential of this research to improve early diagnosis, prevent secondary complications, and enhance the overall quality of life for DED patients in Australia.